TY - JOUR
T1 - Modulating the precision of recurrent bursts in cultured neural networks
AU - Choi, Joon Ho
AU - Kim, June Hoan
AU - Heo, Ryoun
AU - Lee, Kyoung J.
PY - 2012/3/28
Y1 - 2012/3/28
N2 - Synchronized bursts are a very common feature in biological neural networks, and they play an important role in various brain functions and neurological diseases. This Letter investigates "recurrent synchronized bursts" induced by a single pulse stimulation in cultured networks of rat cortical neurons. We look at how the precision in their arrival times can be modified by a noble time-delayed stimulation protocol, which we term as "Δt training." The emergence of recurrent bursts and the change of the precision in their arrival times can be explained by the stochastic resonance of a damped, subthreshold, neural oscillation.
AB - Synchronized bursts are a very common feature in biological neural networks, and they play an important role in various brain functions and neurological diseases. This Letter investigates "recurrent synchronized bursts" induced by a single pulse stimulation in cultured networks of rat cortical neurons. We look at how the precision in their arrival times can be modified by a noble time-delayed stimulation protocol, which we term as "Δt training." The emergence of recurrent bursts and the change of the precision in their arrival times can be explained by the stochastic resonance of a damped, subthreshold, neural oscillation.
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U2 - 10.1103/PhysRevLett.108.138103
DO - 10.1103/PhysRevLett.108.138103
M3 - Article
AN - SCOPUS:84859317477
VL - 108
JO - Physical Review Letters
JF - Physical Review Letters
SN - 0031-9007
IS - 13
M1 - 138103
ER -