Modulating the precision of recurrent bursts in cultured neural networks

Joon Ho Choi, June Hoan Kim, Ryoun Heo, Kyoung Jin Lee

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Synchronized bursts are a very common feature in biological neural networks, and they play an important role in various brain functions and neurological diseases. This Letter investigates "recurrent synchronized bursts" induced by a single pulse stimulation in cultured networks of rat cortical neurons. We look at how the precision in their arrival times can be modified by a noble time-delayed stimulation protocol, which we term as "Δt training." The emergence of recurrent bursts and the change of the precision in their arrival times can be explained by the stochastic resonance of a damped, subthreshold, neural oscillation.

Original languageEnglish
Article number138103
JournalPhysical Review Letters
Issue number13
Publication statusPublished - 2012 Mar 28


ASJC Scopus subject areas

  • Physics and Astronomy(all)

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