Molecular and phylogenetic analyses of influenza B viruses isolated from pediatric inpatients in South Korea during the 2011–2012 winter season

Jeong Hyun Nam, Eun Jung Song, Daesub Song, Erica Españo, Sang Mu Shim, Seo Hee Jeong, Robert G. Webster, Woo Joo Kim, Jeong Ki Kim

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Influenza B virus remains a major cause of respiratory diseases worldwide. Because of limited epidemiological and genetic data, the local and global transmission patterns of influenza B virus are not fully understood. Here we report the molecular and phylogenetic characterization of 163 influenza B virus isolates from pediatric inpatients with influenza-like illness in the winter of 2011–2012 in South Korea. Analysis of haemagglutinin and neuraminidase genes of the influenza B isolates revealed that both B/Victoria (62 %) and B/Yamagata lineages (38 %) co-circulated during that influenza season, and a considerable number of the isolates carried several amino acid substitutions in the four major antigenic epitopes of their haemagglutinin protein.

Original languageEnglish
Article number000983
Pages (from-to)2950-2954
Number of pages5
JournalJournal of General Virology
Volume98
Issue number12
DOIs
Publication statusPublished - 2017 Dec 1

Keywords

  • Influenza B virus
  • Molecular characterization
  • Phylogenetic analysis

ASJC Scopus subject areas

  • Virology

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