Molecular cross talk among the components of the regulatory machinery of mitochondrial structure and quality control

Hyo Min Cho, Woong Sun

Research output: Contribution to journalReview articlepeer-review

3 Citations (Scopus)

Abstract

Mitochondrial dysfunction critically impairs cellular health and often causes or affects the progression of several diseases, including neurodegenerative diseases and cancer. Thus, cells must have several ways to monitor the condition of mitochondrial quality and maintain mitochondrial health. Accumulating evidence suggests that the molecular machinery responding to spontaneous changes in mitochondrial morphology is associated with the routine mitochondrial quality control system. In this short review, we discuss recent progress made in linking mitochondrial structural dynamics and the quality control system.

Original languageEnglish
Pages (from-to)730-737
Number of pages8
JournalExperimental and Molecular Medicine
Volume52
Issue number5
DOIs
Publication statusPublished - 2020 May 1

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Clinical Biochemistry

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