Molecular epidemiology of human adenovirus–associated febrile respiratory illness in soldiers, South Korea

Jung Yeon Heo, Ji Yun Noh, Hye Won Jeong, Kang Won Choe, Joon-Young Song, Woo Joo Kim, Hee-Jin Cheong

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

During January 2013–April 2014, we subjected nasopharyngeal specimens collected from patients with acute febrile respiratory illness in a military hospital to PCR testing to detect 12 respiratory viruses and sequence a partial hexon gene for human adenovirus (HAdV) molecular typing. We analyzed the epidemiologic characteristics of HAdV infections and compared clinical characteristics of HAdV types. Among the 305 patients with acute febrile respiratory illness, we detected respiratory viruses in 139 (45.6%) patients; HAdV was the most prevalent virus (69 cases). Of the 40 adenoviruses identified based on type, HAdV-55 (29 cases) was the most prevalent, followed by HAdV-4 (9 cases). HAdV-55 was common in patients with pneumonia (odds ratio 2.17; 95% CI 0.48–9.86) and hospitalized patients (odds ratio 5.21; 95% CI 1.06–25.50). In soldiers with HAdV infection in Korea, HAdV-55 was the most prevalent type and might be associated with severe clinical outcomes.

Original languageEnglish
Pages (from-to)1221-1227
Number of pages7
JournalEmerging Infectious Diseases
Volume24
Issue number7
DOIs
Publication statusPublished - 2018 Jul 1

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Human Adenoviruses
Republic of Korea
Molecular Epidemiology
Military Personnel
Fever
Human Adenovirus Infections
Viruses
Odds Ratio
Molecular Typing
Military Hospitals
Korea
Adenoviridae
Pneumonia
Polymerase Chain Reaction
Genes

ASJC Scopus subject areas

  • Epidemiology
  • Microbiology (medical)
  • Infectious Diseases

Cite this

Molecular epidemiology of human adenovirus–associated febrile respiratory illness in soldiers, South Korea. / Heo, Jung Yeon; Noh, Ji Yun; Jeong, Hye Won; Choe, Kang Won; Song, Joon-Young; Kim, Woo Joo; Cheong, Hee-Jin.

In: Emerging Infectious Diseases, Vol. 24, No. 7, 01.07.2018, p. 1221-1227.

Research output: Contribution to journalArticle

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