Molecular imaging for In vivo tracking of stem cell fate

Kyoung Soo Lee, Eun Ji Kim, Ji Suk Choi, Ick Chan Kwon, Yong Woo Cho

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Stem cells have a potential to dramatically change the common modalities of treatment for many diseases. Despite their rapid transition from animal studies to clinical applications, a number of unanswered questions remain regarding in vivo behaviors of stem cells transplanted into target tissues, including questions about their survival, distribution, migration, differentiation, and tumorigenicity. Recent advances in noninvasive molecular imaging technologies, including optical imaging, magnetic resonance imaging (MRI), radionuclide imaging, and reporter genebased imaging, have gradually elucidated the fundamental behaviors of stem cells via in vivo real time qualitative and quantitative monitoring. Here, we briefly review current imaging techniques for tracking stem cells, with an emphasis on the advantages and drawbacks of each imaging approach, and discuss future prospects for in vivo tracking of stem cells in regenerative medicine.

[Figure not available: see fulltext.]

Original languageEnglish
Pages (from-to)1141-1151
Number of pages11
JournalMacromolecular Research
Volume22
Issue number11
DOIs
Publication statusPublished - 2014 Jan 1
Externally publishedYes

Fingerprint

Molecular imaging
Stem cells
Imaging techniques
Magnetic resonance
Radioisotopes
Animals
Tissue
Monitoring

Cite this

Lee, K. S., Kim, E. J., Choi, J. S., Kwon, I. C., & Cho, Y. W. (2014). Molecular imaging for In vivo tracking of stem cell fate. Macromolecular Research, 22(11), 1141-1151. https://doi.org/10.1007/s13233-014-2184-9

Molecular imaging for In vivo tracking of stem cell fate. / Lee, Kyoung Soo; Kim, Eun Ji; Choi, Ji Suk; Kwon, Ick Chan; Cho, Yong Woo.

In: Macromolecular Research, Vol. 22, No. 11, 01.01.2014, p. 1141-1151.

Research output: Contribution to journalArticle

Lee, KS, Kim, EJ, Choi, JS, Kwon, IC & Cho, YW 2014, 'Molecular imaging for In vivo tracking of stem cell fate', Macromolecular Research, vol. 22, no. 11, pp. 1141-1151. https://doi.org/10.1007/s13233-014-2184-9
Lee, Kyoung Soo ; Kim, Eun Ji ; Choi, Ji Suk ; Kwon, Ick Chan ; Cho, Yong Woo. / Molecular imaging for In vivo tracking of stem cell fate. In: Macromolecular Research. 2014 ; Vol. 22, No. 11. pp. 1141-1151.
@article{5e6e179714334511bd832efbc10f6636,
title = "Molecular imaging for In vivo tracking of stem cell fate",
abstract = "Stem cells have a potential to dramatically change the common modalities of treatment for many diseases. Despite their rapid transition from animal studies to clinical applications, a number of unanswered questions remain regarding in vivo behaviors of stem cells transplanted into target tissues, including questions about their survival, distribution, migration, differentiation, and tumorigenicity. Recent advances in noninvasive molecular imaging technologies, including optical imaging, magnetic resonance imaging (MRI), radionuclide imaging, and reporter genebased imaging, have gradually elucidated the fundamental behaviors of stem cells via in vivo real time qualitative and quantitative monitoring. Here, we briefly review current imaging techniques for tracking stem cells, with an emphasis on the advantages and drawbacks of each imaging approach, and discuss future prospects for in vivo tracking of stem cells in regenerative medicine.[Figure not available: see fulltext.]",
keywords = "in vivo tracking, molecular imaging, regenerative medicine, stem cell",
author = "Lee, {Kyoung Soo} and Kim, {Eun Ji} and Choi, {Ji Suk} and Kwon, {Ick Chan} and Cho, {Yong Woo}",
year = "2014",
month = "1",
day = "1",
doi = "10.1007/s13233-014-2184-9",
language = "English",
volume = "22",
pages = "1141--1151",
journal = "Macromolecular Research",
issn = "1598-5032",
publisher = "Polymer Society of Korea",
number = "11",

}

TY - JOUR

T1 - Molecular imaging for In vivo tracking of stem cell fate

AU - Lee, Kyoung Soo

AU - Kim, Eun Ji

AU - Choi, Ji Suk

AU - Kwon, Ick Chan

AU - Cho, Yong Woo

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Stem cells have a potential to dramatically change the common modalities of treatment for many diseases. Despite their rapid transition from animal studies to clinical applications, a number of unanswered questions remain regarding in vivo behaviors of stem cells transplanted into target tissues, including questions about their survival, distribution, migration, differentiation, and tumorigenicity. Recent advances in noninvasive molecular imaging technologies, including optical imaging, magnetic resonance imaging (MRI), radionuclide imaging, and reporter genebased imaging, have gradually elucidated the fundamental behaviors of stem cells via in vivo real time qualitative and quantitative monitoring. Here, we briefly review current imaging techniques for tracking stem cells, with an emphasis on the advantages and drawbacks of each imaging approach, and discuss future prospects for in vivo tracking of stem cells in regenerative medicine.[Figure not available: see fulltext.]

AB - Stem cells have a potential to dramatically change the common modalities of treatment for many diseases. Despite their rapid transition from animal studies to clinical applications, a number of unanswered questions remain regarding in vivo behaviors of stem cells transplanted into target tissues, including questions about their survival, distribution, migration, differentiation, and tumorigenicity. Recent advances in noninvasive molecular imaging technologies, including optical imaging, magnetic resonance imaging (MRI), radionuclide imaging, and reporter genebased imaging, have gradually elucidated the fundamental behaviors of stem cells via in vivo real time qualitative and quantitative monitoring. Here, we briefly review current imaging techniques for tracking stem cells, with an emphasis on the advantages and drawbacks of each imaging approach, and discuss future prospects for in vivo tracking of stem cells in regenerative medicine.[Figure not available: see fulltext.]

KW - in vivo tracking

KW - molecular imaging

KW - regenerative medicine

KW - stem cell

UR - http://www.scopus.com/inward/record.url?scp=84912058848&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84912058848&partnerID=8YFLogxK

U2 - 10.1007/s13233-014-2184-9

DO - 10.1007/s13233-014-2184-9

M3 - Article

AN - SCOPUS:84912058848

VL - 22

SP - 1141

EP - 1151

JO - Macromolecular Research

JF - Macromolecular Research

SN - 1598-5032

IS - 11

ER -