Molecular nanoelectronics for label free DNA analysis

L. P. Lee, S. Oh, Yeonho Choi, J. S. Lee

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

An ultrasensitive nanogap junction is developed for label-free biomolecular detection. The nanogap junction can minimize the effects of electrode polarization. Without any label, dielectric detection of DNA hybridization is accomplished: the 70% and 12% changes of capacitance after hybridization were accomplished at 100 Hz for 10 μM and 10 fM concentrations of target DNA, respectively. The nanogap junction-based dielectric DNA detection method and the batch fabrication method of nanogap junctions might able to change the paradigm of functional genomics and proteomics.

Original languageEnglish
Title of host publication2002 International Microprocesses and Nanotechnology Conference, MNC 2002
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages286-287
Number of pages2
ISBN (Electronic)4891140313, 9784891140311
DOIs
Publication statusPublished - 2002
Externally publishedYes
EventInternational Microprocesses and Nanotechnology Conference, MNC 2002 - Tokyo, Japan
Duration: 2002 Nov 62002 Nov 8

Other

OtherInternational Microprocesses and Nanotechnology Conference, MNC 2002
CountryJapan
CityTokyo
Period02/11/602/11/8

ASJC Scopus subject areas

  • Hardware and Architecture
  • Electrical and Electronic Engineering

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  • Cite this

    Lee, L. P., Oh, S., Choi, Y., & Lee, J. S. (2002). Molecular nanoelectronics for label free DNA analysis. In 2002 International Microprocesses and Nanotechnology Conference, MNC 2002 (pp. 286-287). [1178655] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/IMNC.2002.1178655