Mononuclear syndrome with acute hepatitis diagnosed as Mycoplasma pneumoniae infection without lung involvement

Kyoung H. Ko, Ja Kim Min, Seung H. Baik, Young Kyung Yoon

Research output: Contribution to journalArticle

Abstract

Although pneumonia is the hallmark of Mycoplasma pneumoniae infections, it has been associated with protean manifestations such as extrapulmonary involvement. Herein, a rare case of mononuclear syndrome with acute hepatitis and erythema multiforme revealed as M pneumoniae infection without lung involvement is reported. A 30-year-old man, previously healthy, presented with fever and rash with acute hepatitis: AST 603 IU/L, ALT 747 IU/L, prothrombin time 52%. Peripheral blood smears indicated monocytosis with atypical lymphocyte. Bone marrow biopsy revealed increased plasma cell infiltration. M pneumoniae infection was detected by serology testing. After treatment with macrolide, clinical symptoms and signs and serological tests were fully resolved. Diagnosis of this etiologic association is important when patients present with various clinical syndromes without pneumonia, because only specific antimicrobial therapy is effective against M pneumoniae.

Original languageEnglish
Pages (from-to)81-84
Number of pages4
JournalAnnals of Saudi Medicine
Volume36
Issue number1
DOIs
Publication statusPublished - 2016 Jan 1

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Mycoplasma pneumoniae
Hepatitis
Pneumonia
Lung
Infection
Erythema Multiforme
Prothrombin Time
Macrolides
Serologic Tests
Serology
Plasma Cells
Exanthema
Signs and Symptoms
Fever
Bone Marrow
Lymphocytes
Biopsy
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Mononuclear syndrome with acute hepatitis diagnosed as Mycoplasma pneumoniae infection without lung involvement. / Ko, Kyoung H.; Min, Ja Kim; Baik, Seung H.; Yoon, Young Kyung.

In: Annals of Saudi Medicine, Vol. 36, No. 1, 01.01.2016, p. 81-84.

Research output: Contribution to journalArticle

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