MR differentiation of low-grade chondrosarcoma from enchondroma

Bo Bae Choi, Won Hee Jee, Hee Jung Sunwoo, Jae Hyun Cho, Jee Young Kim, Kyung Ah Chun, Suk-Joo Hong, Hye Won Chung, Mi Sook Sung, Yeon Soo Lee, Yang Guk Chung

Research output: Contribution to journalArticle

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Abstract

Purpose: To evaluate magnetic resonance (MR) imaging for the discrimination between low-grade chondrosarcoma and enchondroma. Materials and methods: MR images of 34 patients who were confirmed with low-grade chondrosarcoma or enchondroma were retrospectively reviewed. After review of medical records, MR findings in 18 patients with low-grade chondrosarcoma and 16 patients with enchondroma were compared. MR images were retrospectively reviewed for the lesion location (central or eccentric; epiphysis, metaphysic, or diaphysis), margin, contour, mineralized matrix, endosteal scalloping, cortical expansion, cortical destruction, soft tissue mass formation, and periosteal reaction. Signal intensity, the patterns of contrast enhancement (unilocular or multilobular), soft tissue mass, and adjacent abnormal bone marrow and soft tissue signal were also reviewed. Statistical analysis was performed with chi-square test. Results: The patients with low-grade chondrosarcoma had a significantly higher incidence of MR findings (P< .05): predominantly intermediate signal on T1-weighted images [72% (13/18) in low-grade chondrosarcoma vs. 25% (4/16) in enchondroma], multilocular appearance on contrast-enhanced T1-weighted images [83% (15/18) vs. 44% (7/16)], cortical destruction [33% (6/18) vs. 0% (0/16)], a soft tissue mass [28% (5/18) vs. 0% (0/16)], adjacent bone marrow and soft tissue abnormal signal [22% (4/18) vs. 0% (0/16)], and an involvement of the epiphysis or flat bone [56% (10/18) vs. 19% (3/16)]. Conclusion: MR imaging shows helpful features for differentiating low-grade chondrosarcoma from enchondroma.

Original languageEnglish
Pages (from-to)542-547
Number of pages6
JournalClinical Imaging
Volume37
Issue number3
DOIs
Publication statusPublished - 2013 May 1

Fingerprint

Chondroma
Chondrosarcoma
Magnetic Resonance Spectroscopy
Epiphyses
Metaphysics
Bone Marrow
Magnetic Resonance Imaging
Diaphyses
Chi-Square Distribution
Medical Records
Bone and Bones
Incidence

Keywords

  • Bone
  • Enchondroma
  • Low-grade chondrosarcoma
  • MR imaging
  • Neoplasms
  • Tumors

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Choi, B. B., Jee, W. H., Sunwoo, H. J., Cho, J. H., Kim, J. Y., Chun, K. A., ... Chung, Y. G. (2013). MR differentiation of low-grade chondrosarcoma from enchondroma. Clinical Imaging, 37(3), 542-547. https://doi.org/10.1016/j.clinimag.2012.08.006

MR differentiation of low-grade chondrosarcoma from enchondroma. / Choi, Bo Bae; Jee, Won Hee; Sunwoo, Hee Jung; Cho, Jae Hyun; Kim, Jee Young; Chun, Kyung Ah; Hong, Suk-Joo; Chung, Hye Won; Sung, Mi Sook; Lee, Yeon Soo; Chung, Yang Guk.

In: Clinical Imaging, Vol. 37, No. 3, 01.05.2013, p. 542-547.

Research output: Contribution to journalArticle

Choi, BB, Jee, WH, Sunwoo, HJ, Cho, JH, Kim, JY, Chun, KA, Hong, S-J, Chung, HW, Sung, MS, Lee, YS & Chung, YG 2013, 'MR differentiation of low-grade chondrosarcoma from enchondroma', Clinical Imaging, vol. 37, no. 3, pp. 542-547. https://doi.org/10.1016/j.clinimag.2012.08.006
Choi BB, Jee WH, Sunwoo HJ, Cho JH, Kim JY, Chun KA et al. MR differentiation of low-grade chondrosarcoma from enchondroma. Clinical Imaging. 2013 May 1;37(3):542-547. https://doi.org/10.1016/j.clinimag.2012.08.006
Choi, Bo Bae ; Jee, Won Hee ; Sunwoo, Hee Jung ; Cho, Jae Hyun ; Kim, Jee Young ; Chun, Kyung Ah ; Hong, Suk-Joo ; Chung, Hye Won ; Sung, Mi Sook ; Lee, Yeon Soo ; Chung, Yang Guk. / MR differentiation of low-grade chondrosarcoma from enchondroma. In: Clinical Imaging. 2013 ; Vol. 37, No. 3. pp. 542-547.
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abstract = "Purpose: To evaluate magnetic resonance (MR) imaging for the discrimination between low-grade chondrosarcoma and enchondroma. Materials and methods: MR images of 34 patients who were confirmed with low-grade chondrosarcoma or enchondroma were retrospectively reviewed. After review of medical records, MR findings in 18 patients with low-grade chondrosarcoma and 16 patients with enchondroma were compared. MR images were retrospectively reviewed for the lesion location (central or eccentric; epiphysis, metaphysic, or diaphysis), margin, contour, mineralized matrix, endosteal scalloping, cortical expansion, cortical destruction, soft tissue mass formation, and periosteal reaction. Signal intensity, the patterns of contrast enhancement (unilocular or multilobular), soft tissue mass, and adjacent abnormal bone marrow and soft tissue signal were also reviewed. Statistical analysis was performed with chi-square test. Results: The patients with low-grade chondrosarcoma had a significantly higher incidence of MR findings (P< .05): predominantly intermediate signal on T1-weighted images [72{\%} (13/18) in low-grade chondrosarcoma vs. 25{\%} (4/16) in enchondroma], multilocular appearance on contrast-enhanced T1-weighted images [83{\%} (15/18) vs. 44{\%} (7/16)], cortical destruction [33{\%} (6/18) vs. 0{\%} (0/16)], a soft tissue mass [28{\%} (5/18) vs. 0{\%} (0/16)], adjacent bone marrow and soft tissue abnormal signal [22{\%} (4/18) vs. 0{\%} (0/16)], and an involvement of the epiphysis or flat bone [56{\%} (10/18) vs. 19{\%} (3/16)]. Conclusion: MR imaging shows helpful features for differentiating low-grade chondrosarcoma from enchondroma.",
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AU - Choi, Bo Bae

AU - Jee, Won Hee

AU - Sunwoo, Hee Jung

AU - Cho, Jae Hyun

AU - Kim, Jee Young

AU - Chun, Kyung Ah

AU - Hong, Suk-Joo

AU - Chung, Hye Won

AU - Sung, Mi Sook

AU - Lee, Yeon Soo

AU - Chung, Yang Guk

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N2 - Purpose: To evaluate magnetic resonance (MR) imaging for the discrimination between low-grade chondrosarcoma and enchondroma. Materials and methods: MR images of 34 patients who were confirmed with low-grade chondrosarcoma or enchondroma were retrospectively reviewed. After review of medical records, MR findings in 18 patients with low-grade chondrosarcoma and 16 patients with enchondroma were compared. MR images were retrospectively reviewed for the lesion location (central or eccentric; epiphysis, metaphysic, or diaphysis), margin, contour, mineralized matrix, endosteal scalloping, cortical expansion, cortical destruction, soft tissue mass formation, and periosteal reaction. Signal intensity, the patterns of contrast enhancement (unilocular or multilobular), soft tissue mass, and adjacent abnormal bone marrow and soft tissue signal were also reviewed. Statistical analysis was performed with chi-square test. Results: The patients with low-grade chondrosarcoma had a significantly higher incidence of MR findings (P< .05): predominantly intermediate signal on T1-weighted images [72% (13/18) in low-grade chondrosarcoma vs. 25% (4/16) in enchondroma], multilocular appearance on contrast-enhanced T1-weighted images [83% (15/18) vs. 44% (7/16)], cortical destruction [33% (6/18) vs. 0% (0/16)], a soft tissue mass [28% (5/18) vs. 0% (0/16)], adjacent bone marrow and soft tissue abnormal signal [22% (4/18) vs. 0% (0/16)], and an involvement of the epiphysis or flat bone [56% (10/18) vs. 19% (3/16)]. Conclusion: MR imaging shows helpful features for differentiating low-grade chondrosarcoma from enchondroma.

AB - Purpose: To evaluate magnetic resonance (MR) imaging for the discrimination between low-grade chondrosarcoma and enchondroma. Materials and methods: MR images of 34 patients who were confirmed with low-grade chondrosarcoma or enchondroma were retrospectively reviewed. After review of medical records, MR findings in 18 patients with low-grade chondrosarcoma and 16 patients with enchondroma were compared. MR images were retrospectively reviewed for the lesion location (central or eccentric; epiphysis, metaphysic, or diaphysis), margin, contour, mineralized matrix, endosteal scalloping, cortical expansion, cortical destruction, soft tissue mass formation, and periosteal reaction. Signal intensity, the patterns of contrast enhancement (unilocular or multilobular), soft tissue mass, and adjacent abnormal bone marrow and soft tissue signal were also reviewed. Statistical analysis was performed with chi-square test. Results: The patients with low-grade chondrosarcoma had a significantly higher incidence of MR findings (P< .05): predominantly intermediate signal on T1-weighted images [72% (13/18) in low-grade chondrosarcoma vs. 25% (4/16) in enchondroma], multilocular appearance on contrast-enhanced T1-weighted images [83% (15/18) vs. 44% (7/16)], cortical destruction [33% (6/18) vs. 0% (0/16)], a soft tissue mass [28% (5/18) vs. 0% (0/16)], adjacent bone marrow and soft tissue abnormal signal [22% (4/18) vs. 0% (0/16)], and an involvement of the epiphysis or flat bone [56% (10/18) vs. 19% (3/16)]. Conclusion: MR imaging shows helpful features for differentiating low-grade chondrosarcoma from enchondroma.

KW - Bone

KW - Enchondroma

KW - Low-grade chondrosarcoma

KW - MR imaging

KW - Neoplasms

KW - Tumors

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