MR differentiation of low-grade chondrosarcoma from enchondroma

Bo Bae Choi, Won Hee Jee, Hee Jung Sunwoo, Jae Hyun Cho, Jee Young Kim, Kyung Ah Chun, Suk Joo Hong, Hye Won Chung, Mi Sook Sung, Yeon Soo Lee, Yang Guk Chung

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Abstract

Purpose: To evaluate magnetic resonance (MR) imaging for the discrimination between low-grade chondrosarcoma and enchondroma. Materials and methods: MR images of 34 patients who were confirmed with low-grade chondrosarcoma or enchondroma were retrospectively reviewed. After review of medical records, MR findings in 18 patients with low-grade chondrosarcoma and 16 patients with enchondroma were compared. MR images were retrospectively reviewed for the lesion location (central or eccentric; epiphysis, metaphysic, or diaphysis), margin, contour, mineralized matrix, endosteal scalloping, cortical expansion, cortical destruction, soft tissue mass formation, and periosteal reaction. Signal intensity, the patterns of contrast enhancement (unilocular or multilobular), soft tissue mass, and adjacent abnormal bone marrow and soft tissue signal were also reviewed. Statistical analysis was performed with chi-square test. Results: The patients with low-grade chondrosarcoma had a significantly higher incidence of MR findings (P< .05): predominantly intermediate signal on T1-weighted images [72% (13/18) in low-grade chondrosarcoma vs. 25% (4/16) in enchondroma], multilocular appearance on contrast-enhanced T1-weighted images [83% (15/18) vs. 44% (7/16)], cortical destruction [33% (6/18) vs. 0% (0/16)], a soft tissue mass [28% (5/18) vs. 0% (0/16)], adjacent bone marrow and soft tissue abnormal signal [22% (4/18) vs. 0% (0/16)], and an involvement of the epiphysis or flat bone [56% (10/18) vs. 19% (3/16)]. Conclusion: MR imaging shows helpful features for differentiating low-grade chondrosarcoma from enchondroma.

Original languageEnglish
Pages (from-to)542-547
Number of pages6
JournalClinical Imaging
Volume37
Issue number3
DOIs
Publication statusPublished - 2013 May

Keywords

  • Bone
  • Enchondroma
  • Low-grade chondrosarcoma
  • MR imaging
  • Neoplasms
  • Tumors

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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    Choi, B. B., Jee, W. H., Sunwoo, H. J., Cho, J. H., Kim, J. Y., Chun, K. A., Hong, S. J., Chung, H. W., Sung, M. S., Lee, Y. S., & Chung, Y. G. (2013). MR differentiation of low-grade chondrosarcoma from enchondroma. Clinical Imaging, 37(3), 542-547. https://doi.org/10.1016/j.clinimag.2012.08.006