Multi-component nanorods for vaccination applications

A. K. Salem, C. F. Hung, Tae Woo Kim, T. C. Wu, P. C. Searson, K. W. Leong

Research output: Contribution to journalArticle

55 Citations (Scopus)

Abstract

Immune responses from Au/Ni nanorods prepared by electrochemical deposition in alumina templates are evaluated in C57BL/6 mice. When the nanorods are bombarded into skin, they generate a strong CDS T-cell and antibody response. When pcDNA3 is bound to the Ni segment of the nanorod, it provides a strong immunostimulatory adjuvant effect to the antigen bound on the Au segment.

Original languageEnglish
Pages (from-to)484-487
Number of pages4
JournalNanotechnology
Volume16
Issue number4
DOIs
Publication statusPublished - 2005 Apr 1
Externally publishedYes

Fingerprint

Nanotubes
Nanorods
nanorods
Vaccination
T-cells
Aluminum Oxide
antigens
Antigens
antibodies
Inbred C57BL Mouse
Antibodies
Antibody Formation
mice
Skin
Alumina
templates
aluminum oxides
T-Lymphocytes

ASJC Scopus subject areas

  • Engineering (miscellaneous)
  • Materials Science(all)
  • Physics and Astronomy (miscellaneous)

Cite this

Salem, A. K., Hung, C. F., Kim, T. W., Wu, T. C., Searson, P. C., & Leong, K. W. (2005). Multi-component nanorods for vaccination applications. Nanotechnology, 16(4), 484-487. https://doi.org/10.1088/0957-4484/16/4/025

Multi-component nanorods for vaccination applications. / Salem, A. K.; Hung, C. F.; Kim, Tae Woo; Wu, T. C.; Searson, P. C.; Leong, K. W.

In: Nanotechnology, Vol. 16, No. 4, 01.04.2005, p. 484-487.

Research output: Contribution to journalArticle

Salem, AK, Hung, CF, Kim, TW, Wu, TC, Searson, PC & Leong, KW 2005, 'Multi-component nanorods for vaccination applications', Nanotechnology, vol. 16, no. 4, pp. 484-487. https://doi.org/10.1088/0957-4484/16/4/025
Salem AK, Hung CF, Kim TW, Wu TC, Searson PC, Leong KW. Multi-component nanorods for vaccination applications. Nanotechnology. 2005 Apr 1;16(4):484-487. https://doi.org/10.1088/0957-4484/16/4/025
Salem, A. K. ; Hung, C. F. ; Kim, Tae Woo ; Wu, T. C. ; Searson, P. C. ; Leong, K. W. / Multi-component nanorods for vaccination applications. In: Nanotechnology. 2005 ; Vol. 16, No. 4. pp. 484-487.
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