Multidrug-resistant pulmonary tuberculosis among young Korean soldiers in a communal setting

Sei Won Lee, Kyeongman Jeon, Kwang Hyun Kim, Kyung Hoon Min

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

The goal of this study was to evaluate the prevalence of first-line anti-tuberculosis drug resistance and risk factors associated with multidrug-resistant tuberculosis (MDR TB) among young soldiers in the Korean military, which has a strict tuberculosis control program. All patients with culture-confirmed pulmonary tuberculosis during their service at the Armed Forces Capital Hospital from January 2001 to December 2006 were enrolled in the study. Drug resistant Mycobacterium tuberculosis was isolated from 18 patients (12.2%) and multidrug-resistant M. tuberculosis was isolated from 12 patients (8.1%). Previous treatment of tuberculosis and the presence of a cavity on the patient's chest computed tomography scan were associated with MDR TB; military rank, smoking habits, and positive acid-fast bacilli smears were not associated with MDR TB. In a multiple logistic regression analysis, previous treatment of tuberculosis was a significant independent risk factor for MDR TB (odds ratio 6.12, 95% confidence interval 1.53-24.46). The prevalence of drug resistant tuberculosis among young soldiers in the Korean military was moderately high and the majority of resistant cases were found in patients who had undergone previous treatment of tuberculosis. Based on our results, we suggest that relapsed tuberculosis cases within communal settings should be cautiously managed until the drug susceptibility tests report is completed, even if previous treatment results were satisfactory.

Original languageEnglish
Pages (from-to)592-595
Number of pages4
JournalJournal of Korean medical science
Volume24
Issue number4
DOIs
Publication statusPublished - 2009 Aug

Keywords

  • Korea
  • Military personnel
  • Tuberculosis, Multidrug-resistant
  • Tuberculosis, Pulmonary

ASJC Scopus subject areas

  • Medicine(all)

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