Multifunctional chitosan nanoparticles for tumor imaging and therapy

Ji Young Yhee, Heebeom Koo, Dong Eun Lee, Kuiwon Choi, Ick Chan Kwon, Kwang Meyung Kim

Research output: Chapter in Book/Report/Conference proceedingChapter

15 Citations (Scopus)

Abstract

Chitosan and its derivatives have been widely used for various biomedical applications because of their unique chemical and biological characters. The amine groups in the backbone of chitosan allow chemical modification to change the physical properties of chitosan. Based on hydrophobic or charge interactions with this chitosan polymer backbone, stable self-assembled nanoparticles can be fabricated in aqueous condition. These nanosized structures enable intravenous injection and show large accumulation in tumor tissue, indicating great potential in imaging and drug delivery. The main objective of this review is to introduce various chitosan nanoparticles and their recent applications for tumor diagnosis and therapy.

Original languageEnglish
Title of host publicationAdvances in Polymer Science
Pages139-162
Number of pages24
Volume243
Edition1
DOIs
Publication statusPublished - 2011 Sep 6
Externally publishedYes

Publication series

NameAdvances in Polymer Science
Number1
Volume243
ISSN (Print)00653195

Fingerprint

Chitosan
Tumors
Nanoparticles
Imaging techniques
Chemical modification
Drug delivery
Amines
Polymers
Physical properties
Tissue
Derivatives

Keywords

  • Chitosan
  • Molecular imaging
  • Nanoparticle
  • Tumor

ASJC Scopus subject areas

  • Organic Chemistry
  • Polymers and Plastics
  • Chemical Engineering(all)

Cite this

Yhee, J. Y., Koo, H., Lee, D. E., Choi, K., Kwon, I. C., & Kim, K. M. (2011). Multifunctional chitosan nanoparticles for tumor imaging and therapy. In Advances in Polymer Science (1 ed., Vol. 243, pp. 139-162). (Advances in Polymer Science; Vol. 243, No. 1). https://doi.org/10.1007/12_2011_119

Multifunctional chitosan nanoparticles for tumor imaging and therapy. / Yhee, Ji Young; Koo, Heebeom; Lee, Dong Eun; Choi, Kuiwon; Kwon, Ick Chan; Kim, Kwang Meyung.

Advances in Polymer Science. Vol. 243 1. ed. 2011. p. 139-162 (Advances in Polymer Science; Vol. 243, No. 1).

Research output: Chapter in Book/Report/Conference proceedingChapter

Yhee, JY, Koo, H, Lee, DE, Choi, K, Kwon, IC & Kim, KM 2011, Multifunctional chitosan nanoparticles for tumor imaging and therapy. in Advances in Polymer Science. 1 edn, vol. 243, Advances in Polymer Science, no. 1, vol. 243, pp. 139-162. https://doi.org/10.1007/12_2011_119
Yhee JY, Koo H, Lee DE, Choi K, Kwon IC, Kim KM. Multifunctional chitosan nanoparticles for tumor imaging and therapy. In Advances in Polymer Science. 1 ed. Vol. 243. 2011. p. 139-162. (Advances in Polymer Science; 1). https://doi.org/10.1007/12_2011_119
Yhee, Ji Young ; Koo, Heebeom ; Lee, Dong Eun ; Choi, Kuiwon ; Kwon, Ick Chan ; Kim, Kwang Meyung. / Multifunctional chitosan nanoparticles for tumor imaging and therapy. Advances in Polymer Science. Vol. 243 1. ed. 2011. pp. 139-162 (Advances in Polymer Science; 1).
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