Abstract
(Figure Presented) Diagnosis and treatment all in one: Multifunctional magneto-polymeric nanohybrids (MMPNs) have been synthesized using ultrasensitive MnFe2O4 nanocrystals, chemotherapeutic agents, and encapsulating amphiphilic block copolymers for targeted detection by MRI and treatment of breast cancer. See the TEM image (left) of an MMPN and T 2-weighted MR images (top row) and color map (bottom row) of the relaxivity R2 for NIH3T6.7 and MDA-MB-231 cells.
| Original language | English |
|---|---|
| Pages (from-to) | 8836-8839 |
| Number of pages | 4 |
| Journal | Angewandte Chemie - International Edition |
| Volume | 46 |
| Issue number | 46 |
| DOIs | |
| Publication status | Published - 2007 Dec 10 |
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Keywords
- Drug delivery
- Hybrid composites
- Imaging agents
- Magnetic resonance
- Transmission electron microscopy
ASJC Scopus subject areas
- Chemistry(all)
Cite this
Multifunctional magneto-polymeric nanohybrids for targeted detection and synergistic therapeutic effects on breast cancer. / Yang, Jaemoon; Lee, Choong Hwan; Ko, Hyun Ju; Suh, Jin Suck; Yoon, Ho Geun; Lee, Kwangyeol; Huh, Yong Min; Haam, Seungjoo.
In: Angewandte Chemie - International Edition, Vol. 46, No. 46, 10.12.2007, p. 8836-8839.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Multifunctional magneto-polymeric nanohybrids for targeted detection and synergistic therapeutic effects on breast cancer
AU - Yang, Jaemoon
AU - Lee, Choong Hwan
AU - Ko, Hyun Ju
AU - Suh, Jin Suck
AU - Yoon, Ho Geun
AU - Lee, Kwangyeol
AU - Huh, Yong Min
AU - Haam, Seungjoo
PY - 2007/12/10
Y1 - 2007/12/10
N2 - (Figure Presented) Diagnosis and treatment all in one: Multifunctional magneto-polymeric nanohybrids (MMPNs) have been synthesized using ultrasensitive MnFe2O4 nanocrystals, chemotherapeutic agents, and encapsulating amphiphilic block copolymers for targeted detection by MRI and treatment of breast cancer. See the TEM image (left) of an MMPN and T 2-weighted MR images (top row) and color map (bottom row) of the relaxivity R2 for NIH3T6.7 and MDA-MB-231 cells.
AB - (Figure Presented) Diagnosis and treatment all in one: Multifunctional magneto-polymeric nanohybrids (MMPNs) have been synthesized using ultrasensitive MnFe2O4 nanocrystals, chemotherapeutic agents, and encapsulating amphiphilic block copolymers for targeted detection by MRI and treatment of breast cancer. See the TEM image (left) of an MMPN and T 2-weighted MR images (top row) and color map (bottom row) of the relaxivity R2 for NIH3T6.7 and MDA-MB-231 cells.
KW - Drug delivery
KW - Hybrid composites
KW - Imaging agents
KW - Magnetic resonance
KW - Transmission electron microscopy
UR - http://www.scopus.com/inward/record.url?scp=36749044732&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=36749044732&partnerID=8YFLogxK
U2 - 10.1002/anie.200703554
DO - 10.1002/anie.200703554
M3 - Article
C2 - 17943947
AN - SCOPUS:36749044732
VL - 46
SP - 8836
EP - 8839
JO - Angewandte Chemie - International Edition
JF - Angewandte Chemie - International Edition
SN - 1433-7851
IS - 46
ER -