Abstract
(Figure Presented) Diagnosis and treatment all in one: Multifunctional magneto-polymeric nanohybrids (MMPNs) have been synthesized using ultrasensitive MnFe2O4 nanocrystals, chemotherapeutic agents, and encapsulating amphiphilic block copolymers for targeted detection by MRI and treatment of breast cancer. See the TEM image (left) of an MMPN and T 2-weighted MR images (top row) and color map (bottom row) of the relaxivity R2 for NIH3T6.7 and MDA-MB-231 cells.
| Original language | English |
|---|---|
| Pages (from-to) | 8836-8839 |
| Number of pages | 4 |
| Journal | Angewandte Chemie - International Edition |
| Volume | 46 |
| Issue number | 46 |
| DOIs | |
| Publication status | Published - 2007 Dec 10 |
Keywords
- Drug delivery
- Hybrid composites
- Imaging agents
- Magnetic resonance
- Transmission electron microscopy
ASJC Scopus subject areas
- Chemistry(all)
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Cite this
Yang, J., Lee, C. H., Ko, H. J., Suh, J. S., Yoon, H. G., Lee, K., Huh, Y. M., & Haam, S. (2007). Multifunctional magneto-polymeric nanohybrids for targeted detection and synergistic therapeutic effects on breast cancer. Angewandte Chemie - International Edition, 46(46), 8836-8839. https://doi.org/10.1002/anie.200703554