Multiplexed DNA detection with biobarcoded nanoparticle probes

Savka I. Stoeva, Jae Seung Lee, C. Shad Thaxton, Chad A. Mirkin

Research output: Contribution to journalArticle

218 Citations (Scopus)

Abstract

(Figure Presented) Sorting the mail: A highly selective assay for the detection of multiple DNA targets in solution was developed based on gold nanoparticles with oligonucleotide reporters. Four DNA targets associated with infectious viruses were detected simultaneously without enzymatic amplification at mid-femtomolar concentrations.

Original languageEnglish
Pages (from-to)3303-3306
Number of pages4
JournalAngewandte Chemie - International Edition
Volume45
Issue number20
DOIs
Publication statusPublished - 2006 May 12

Keywords

  • Barcodes
  • Biosensors
  • DNA detection
  • Gold
  • Nanoparticles

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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