Multiplexed DNA detection with biobarcoded nanoparticle probes

Savka I. Stoeva; Jae Seung Lee; C. Shad Thaxton; Chad A. Mirkin

doi:10.1002/anie.200600124

Multiplexed DNA detection with biobarcoded nanoparticle probes

Savka I. Stoeva, Jae Seung Lee, C. Shad Thaxton, Chad A. Mirkin

Research output: Contribution to journal › Article › peer-review

237 Citations (Scopus)

Abstract

(Figure Presented) Sorting the mail: A highly selective assay for the detection of multiple DNA targets in solution was developed based on gold nanoparticles with oligonucleotide reporters. Four DNA targets associated with infectious viruses were detected simultaneously without enzymatic amplification at mid-femtomolar concentrations.

Original language	English
Pages (from-to)	3303-3306
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	45
Issue number	20
DOIs	https://doi.org/10.1002/anie.200600124
Publication status	Published - 2006 May 12
Externally published	Yes

Keywords

Barcodes
Biosensors
DNA detection
Gold
Nanoparticles

ASJC Scopus subject areas

Catalysis
Chemistry(all)

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10.1002/anie.200600124

Cite this

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title = "Multiplexed DNA detection with biobarcoded nanoparticle probes",

abstract = "(Figure Presented) Sorting the mail: A highly selective assay for the detection of multiple DNA targets in solution was developed based on gold nanoparticles with oligonucleotide reporters. Four DNA targets associated with infectious viruses were detected simultaneously without enzymatic amplification at mid-femtomolar concentrations.",

keywords = "Barcodes, Biosensors, DNA detection, Gold, Nanoparticles",

author = "Stoeva, {Savka I.} and Lee, {Jae Seung} and Thaxton, {C. Shad} and Mirkin, {Chad A.}",

year = "2006",

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AU - Stoeva, Savka I.

AU - Lee, Jae Seung

AU - Thaxton, C. Shad

AU - Mirkin, Chad A.

PY - 2006/5/12

Y1 - 2006/5/12

N2 - (Figure Presented) Sorting the mail: A highly selective assay for the detection of multiple DNA targets in solution was developed based on gold nanoparticles with oligonucleotide reporters. Four DNA targets associated with infectious viruses were detected simultaneously without enzymatic amplification at mid-femtomolar concentrations.

AB - (Figure Presented) Sorting the mail: A highly selective assay for the detection of multiple DNA targets in solution was developed based on gold nanoparticles with oligonucleotide reporters. Four DNA targets associated with infectious viruses were detected simultaneously without enzymatic amplification at mid-femtomolar concentrations.

KW - Barcodes

KW - Biosensors

KW - DNA detection

KW - Gold

KW - Nanoparticles

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M3 - Article

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ER -

Multiplexed DNA detection with biobarcoded nanoparticle probes

Abstract

Keywords

ASJC Scopus subject areas

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