Multiplexed DNA detection with biobarcoded nanoparticle probes

Savka I. Stoeva, Jae-Seung Lee, C. Shad Thaxton, Chad A. Mirkin

Research output: Contribution to journalArticle

217 Citations (Scopus)

Abstract

(Figure Presented) Sorting the mail: A highly selective assay for the detection of multiple DNA targets in solution was developed based on gold nanoparticles with oligonucleotide reporters. Four DNA targets associated with infectious viruses were detected simultaneously without enzymatic amplification at mid-femtomolar concentrations.

Original languageEnglish
Pages (from-to)3303-3306
Number of pages4
JournalAngewandte Chemie - International Edition
Volume45
Issue number20
DOIs
Publication statusPublished - 2006 May 12
Externally publishedYes

Fingerprint

DNA
Nanoparticles
Oligonucleotides
Viruses
Sorting
Gold
Amplification
Assays

Keywords

  • Barcodes
  • Biosensors
  • DNA detection
  • Gold
  • Nanoparticles

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Multiplexed DNA detection with biobarcoded nanoparticle probes. / Stoeva, Savka I.; Lee, Jae-Seung; Thaxton, C. Shad; Mirkin, Chad A.

In: Angewandte Chemie - International Edition, Vol. 45, No. 20, 12.05.2006, p. 3303-3306.

Research output: Contribution to journalArticle

Stoeva, Savka I. ; Lee, Jae-Seung ; Thaxton, C. Shad ; Mirkin, Chad A. / Multiplexed DNA detection with biobarcoded nanoparticle probes. In: Angewandte Chemie - International Edition. 2006 ; Vol. 45, No. 20. pp. 3303-3306.
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