Myxoid liposarcoma with cartilaginous differentiation: A case study with cytogenetical analysis

Hyunchul Kim, Won Hwangbo, Sangjeong Ahn, Suhjin Kim, Insun Kim, Chul Hwan Kim

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Myxoid liposarcoma is a subtype of liposarcoma. This specific subtype can be identified based on its characteristic histological and cytogenetical features. The tumor has a fusion transcript of the CHOP and TLS genes, which is caused by t(12;16)(q13;p11). Most of the fusion transcripts that have been identified fall into three categories, specifically type I (exons 7-2), type II (exons 5-2), and type III (exons 8-2). A total of seven myxoid liposarcomas associated with the rare phenomenon of cartilaginous differentiation have been documented in the literature. Currently, only one of these cases has been cytogenetically analyzed, and the analysis indicated that it was a type II TLS-CHOP fusion transcript in both the typical myxoid liposarcoma and cartilaginous areas. This study presents a second report of myxoid liposarcoma with cartilaginous differentiation, and includes a cytogenetical analysis of both the myxoid and cartilaginous areas.

Original languageEnglish
Pages (from-to)284-288
Number of pages5
JournalKorean Journal of Pathology
Volume47
Issue number3
DOIs
Publication statusPublished - 2013 Aug 27

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Myxoid Liposarcoma
Exons
Liposarcoma
Genes
Neoplasms

Keywords

  • Cartilage
  • Cartilaginous differentiation
  • Heterologous component
  • Liposarcoma, myxoid
  • TLS/CHOP fusion transcript

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Myxoid liposarcoma with cartilaginous differentiation : A case study with cytogenetical analysis. / Kim, Hyunchul; Hwangbo, Won; Ahn, Sangjeong; Kim, Suhjin; Kim, Insun; Kim, Chul Hwan.

In: Korean Journal of Pathology, Vol. 47, No. 3, 27.08.2013, p. 284-288.

Research output: Contribution to journalArticle

Kim, Hyunchul ; Hwangbo, Won ; Ahn, Sangjeong ; Kim, Suhjin ; Kim, Insun ; Kim, Chul Hwan. / Myxoid liposarcoma with cartilaginous differentiation : A case study with cytogenetical analysis. In: Korean Journal of Pathology. 2013 ; Vol. 47, No. 3. pp. 284-288.
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