Nafion-stabilized two-dimensional transition metal carbide (Ti3C2Tx MXene) as a high-performance electrochemical sensor for neurotransmitter

Faisal Shahzad, Aamir Iqbal, Shabi Abbas Zaidi, Suk-Won Hwang, Chong Min Koo

Research output: Contribution to journalArticle

Abstract

Herein, we demonstrate the selective sensing of Dopamine (DA), an important neurotransmitter, by using Nafion-stabilized two-dimensional transition metal carbides (Ti3C2Tx MXenes). Ti3C2Tx was deposited on a glassy carbon electrode followed by Nafion coating to achieve a robust sensitivity (∼3 nM), good selectivity, wide detection window (0.015–10 μM), high stability, reproducibility, and outstanding recoveries for DA detection in real samples. MXene-based biosensor exhibited much better electrochemical performance when compared with reduced graphene oxide-based biosensor under similar experimental conditions due to the MXenes good electrical conductivity and negatively charged surface which assisted in the selective and sensitive detection of DA.

Original languageEnglish
JournalJournal of Industrial and Engineering Chemistry
DOIs
Publication statusPublished - 2019 Jan 1

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Electrochemical sensors
Transition metals
Neurotransmitter Agents
Carbides
Dopamine
Biosensors
Graphite
Glassy carbon
Oxides
Graphene
Recovery
Coatings
Electrodes
perfluorosulfonic acid

Keywords

  • Dopamine
  • Electrochemical sensor
  • MXenes
  • TiC
  • Two-dimensional transition metal carbides

ASJC Scopus subject areas

  • Chemical Engineering(all)

Cite this

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title = "Nafion-stabilized two-dimensional transition metal carbide (Ti3C2Tx MXene) as a high-performance electrochemical sensor for neurotransmitter",
abstract = "Herein, we demonstrate the selective sensing of Dopamine (DA), an important neurotransmitter, by using Nafion-stabilized two-dimensional transition metal carbides (Ti3C2Tx MXenes). Ti3C2Tx was deposited on a glassy carbon electrode followed by Nafion coating to achieve a robust sensitivity (∼3 nM), good selectivity, wide detection window (0.015–10 μM), high stability, reproducibility, and outstanding recoveries for DA detection in real samples. MXene-based biosensor exhibited much better electrochemical performance when compared with reduced graphene oxide-based biosensor under similar experimental conditions due to the MXenes good electrical conductivity and negatively charged surface which assisted in the selective and sensitive detection of DA.",
keywords = "Dopamine, Electrochemical sensor, MXenes, TiC, Two-dimensional transition metal carbides",
author = "Faisal Shahzad and Aamir Iqbal and Zaidi, {Shabi Abbas} and Suk-Won Hwang and Koo, {Chong Min}",
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T1 - Nafion-stabilized two-dimensional transition metal carbide (Ti3C2Tx MXene) as a high-performance electrochemical sensor for neurotransmitter

AU - Shahzad, Faisal

AU - Iqbal, Aamir

AU - Zaidi, Shabi Abbas

AU - Hwang, Suk-Won

AU - Koo, Chong Min

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Y1 - 2019/1/1

N2 - Herein, we demonstrate the selective sensing of Dopamine (DA), an important neurotransmitter, by using Nafion-stabilized two-dimensional transition metal carbides (Ti3C2Tx MXenes). Ti3C2Tx was deposited on a glassy carbon electrode followed by Nafion coating to achieve a robust sensitivity (∼3 nM), good selectivity, wide detection window (0.015–10 μM), high stability, reproducibility, and outstanding recoveries for DA detection in real samples. MXene-based biosensor exhibited much better electrochemical performance when compared with reduced graphene oxide-based biosensor under similar experimental conditions due to the MXenes good electrical conductivity and negatively charged surface which assisted in the selective and sensitive detection of DA.

AB - Herein, we demonstrate the selective sensing of Dopamine (DA), an important neurotransmitter, by using Nafion-stabilized two-dimensional transition metal carbides (Ti3C2Tx MXenes). Ti3C2Tx was deposited on a glassy carbon electrode followed by Nafion coating to achieve a robust sensitivity (∼3 nM), good selectivity, wide detection window (0.015–10 μM), high stability, reproducibility, and outstanding recoveries for DA detection in real samples. MXene-based biosensor exhibited much better electrochemical performance when compared with reduced graphene oxide-based biosensor under similar experimental conditions due to the MXenes good electrical conductivity and negatively charged surface which assisted in the selective and sensitive detection of DA.

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KW - MXenes

KW - TiC

KW - Two-dimensional transition metal carbides

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