Nano web based novel microchip for artificial kidney

Kwang Ho Lee, Duck Joong Kim, Byoung Goo Min, Sang Hoon Lee

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this study, a novel artificial renal replacement system is presented using a biocompatible polymeric nanofibers and MEMS technology. Usually, a classical artificial renal replacement system employs a semi-permeable membrane based hemodialyzer that replaces an ability of the kidney by removing metabolic toxins through diffusion and hydraulic pressure gradients. But, it has some limits in efficient filtration of metabolic byproducts (e.g.: urea, creatinine, and so on). We have developed PDMS based artificial renal microchips integrating biocompatible polymeric nanofibers which are utilized for the filtration of blood. Here, we demonstrate a new artificial renal chip by integrating a high efficient biocompatible polymeric nanofibers membrane with the PDMS based micro - fluidic platform. Via the optimization of PDMS micro fluidic channel network and the multiple packaging of nanofibers membrane, we will realize the portable and wearable artificial kidney system.

Original languageEnglish
Title of host publicationIFMBE Proceedings
PublisherSpringer Verlag
Pages279-282
Number of pages4
Volume14
Edition1
Publication statusPublished - 2007
Externally publishedYes
Event10th World Congress on Medical Physics and Biomedical Engineering, WC 2006 - Seoul, Korea, Republic of
Duration: 2006 Aug 272006 Sep 1

Other

Other10th World Congress on Medical Physics and Biomedical Engineering, WC 2006
CountryKorea, Republic of
CitySeoul
Period06/8/2706/9/1

Fingerprint

Nanofibers
Fluidics
Membranes
Hemodialyzers
Pressure gradient
Urea
MEMS
Byproducts
Creatinine
Packaging
Blood
Hydraulics

Keywords

  • Artificial kidney
  • Nanofiber
  • PDMS
  • Renal chip

ASJC Scopus subject areas

  • Biomedical Engineering
  • Bioengineering

Cite this

Lee, K. H., Kim, D. J., Min, B. G., & Lee, S. H. (2007). Nano web based novel microchip for artificial kidney. In IFMBE Proceedings (1 ed., Vol. 14, pp. 279-282). Springer Verlag.

Nano web based novel microchip for artificial kidney. / Lee, Kwang Ho; Kim, Duck Joong; Min, Byoung Goo; Lee, Sang Hoon.

IFMBE Proceedings. Vol. 14 1. ed. Springer Verlag, 2007. p. 279-282.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Lee, KH, Kim, DJ, Min, BG & Lee, SH 2007, Nano web based novel microchip for artificial kidney. in IFMBE Proceedings. 1 edn, vol. 14, Springer Verlag, pp. 279-282, 10th World Congress on Medical Physics and Biomedical Engineering, WC 2006, Seoul, Korea, Republic of, 06/8/27.
Lee KH, Kim DJ, Min BG, Lee SH. Nano web based novel microchip for artificial kidney. In IFMBE Proceedings. 1 ed. Vol. 14. Springer Verlag. 2007. p. 279-282
Lee, Kwang Ho ; Kim, Duck Joong ; Min, Byoung Goo ; Lee, Sang Hoon. / Nano web based novel microchip for artificial kidney. IFMBE Proceedings. Vol. 14 1. ed. Springer Verlag, 2007. pp. 279-282
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