Abstract
In this study, a novel artificial renal replacement system is presented using a biocompatible polymeric nanofibers and MEMS technology. Usually, a classical artificial renal replacement system employs a semi-permeable membrane based hemodialyzer that replaces an ability of the kidney by removing metabolic toxins through diffusion and hydraulic pressure gradients. But, it has some limits in efficient filtration of metabolic byproducts (e.g.: urea, creatinine, and so on). We have developed PDMS based artificial renal microchips integrating biocompatible polymeric nanofibers which are utilized for the filtration of blood. Here, we demonstrate a new artificial renal chip by integrating a high efficient biocompatible polymeric nanofibers membrane with the PDMS based micro - fluidic platform. Via the optimization of PDMS micro fluidic channel network and the multiple packaging of nanofibers membrane, we will realize the portable and wearable artificial kidney system.
| Original language | English |
|---|---|
| Title of host publication | IFMBE Proceedings |
| Publisher | Springer Verlag |
| Pages | 279-282 |
| Number of pages | 4 |
| Volume | 14 |
| Edition | 1 |
| Publication status | Published - 2007 |
| Externally published | Yes |
| Event | 10th World Congress on Medical Physics and Biomedical Engineering, WC 2006 - Seoul, Korea, Republic of Duration: 2006 Aug 27 → 2006 Sep 1 |
Other
| Other | 10th World Congress on Medical Physics and Biomedical Engineering, WC 2006 |
|---|---|
| Country | Korea, Republic of |
| City | Seoul |
| Period | 06/8/27 → 06/9/1 |
Fingerprint
Keywords
- Artificial kidney
- Nanofiber
- PDMS
- Renal chip
ASJC Scopus subject areas
- Biomedical Engineering
- Bioengineering
Cite this
Nano web based novel microchip for artificial kidney. / Lee, Kwang Ho; Kim, Duck Joong; Min, Byoung Goo; Lee, Sang Hoon.
IFMBE Proceedings. Vol. 14 1. ed. Springer Verlag, 2007. p. 279-282.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Nano web based novel microchip for artificial kidney
AU - Lee, Kwang Ho
AU - Kim, Duck Joong
AU - Min, Byoung Goo
AU - Lee, Sang Hoon
PY - 2007
Y1 - 2007
N2 - In this study, a novel artificial renal replacement system is presented using a biocompatible polymeric nanofibers and MEMS technology. Usually, a classical artificial renal replacement system employs a semi-permeable membrane based hemodialyzer that replaces an ability of the kidney by removing metabolic toxins through diffusion and hydraulic pressure gradients. But, it has some limits in efficient filtration of metabolic byproducts (e.g.: urea, creatinine, and so on). We have developed PDMS based artificial renal microchips integrating biocompatible polymeric nanofibers which are utilized for the filtration of blood. Here, we demonstrate a new artificial renal chip by integrating a high efficient biocompatible polymeric nanofibers membrane with the PDMS based micro - fluidic platform. Via the optimization of PDMS micro fluidic channel network and the multiple packaging of nanofibers membrane, we will realize the portable and wearable artificial kidney system.
AB - In this study, a novel artificial renal replacement system is presented using a biocompatible polymeric nanofibers and MEMS technology. Usually, a classical artificial renal replacement system employs a semi-permeable membrane based hemodialyzer that replaces an ability of the kidney by removing metabolic toxins through diffusion and hydraulic pressure gradients. But, it has some limits in efficient filtration of metabolic byproducts (e.g.: urea, creatinine, and so on). We have developed PDMS based artificial renal microchips integrating biocompatible polymeric nanofibers which are utilized for the filtration of blood. Here, we demonstrate a new artificial renal chip by integrating a high efficient biocompatible polymeric nanofibers membrane with the PDMS based micro - fluidic platform. Via the optimization of PDMS micro fluidic channel network and the multiple packaging of nanofibers membrane, we will realize the portable and wearable artificial kidney system.
KW - Artificial kidney
KW - Nanofiber
KW - PDMS
KW - Renal chip
UR - http://www.scopus.com/inward/record.url?scp=84958251802&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84958251802&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:84958251802
VL - 14
SP - 279
EP - 282
BT - IFMBE Proceedings
PB - Springer Verlag
ER -