(Figure Presented) A bubbly personality: Coalescence and fusion of carbon dioxide nanobubbles in a tumor leads to microbubbles that can be imaged by ultrasound (see picture). The bubbles are released from gas-generating polymeric nanoparticles that are coated with hydrophobically modified chitosan. Hydrolysis of the polymer poly(BL-PO), which consists of a biodegradable main backbone and a carbonate side chain, results in the release of carbon dioxide.
|Number of pages||5|
|Journal||Angewandte Chemie - International Edition|
|Publication status||Published - 2010 Jan 12|
- Carbon dioxide
- Imaging agents
ASJC Scopus subject areas