Nanomechanical microcantilever for In-Vitro biomolecular detection

Kilho Eom, Tae Yun Kwon, Jinsung Park, Sungsoo Na, Dae Sung Yoon, Tae Song Kim

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Nanomechanical microcantilevers have enabled the sensitive label-free detection of chemical and/or biological molecules. In recent years, resonating microcantilevers have achieved the unprecedented sensitivity in detecting molecules. In this article, we review our current works on the label-free detection of biomolecules based on resonating microcantilevers. Our piezoelectric thick film microcantilevers exhibit the relatively high quality factor in a viscous liquid, indicating the potential of our cantilever to in situ biosensor applications for real-time detection of biomolecular interactions. It is shown that our microcantilevers allow the noise-free real-time monitoring of biomolecular recognitions, providing the insight into kinetics of biomolecular recognitions.

Original languageEnglish
Title of host publicationProceedings of the ASME International Mechanical Engineering Congress and Exposition, IMECE 2007
Pages821-842
Number of pages22
DOIs
Publication statusPublished - 2008
EventASME International Mechanical Engineering Congress and Exposition, IMECE 2007 - Seattle, WA, United States
Duration: 2007 Nov 112007 Nov 15

Publication series

NameASME International Mechanical Engineering Congress and Exposition, Proceedings
Volume10 PART B

Other

OtherASME International Mechanical Engineering Congress and Exposition, IMECE 2007
CountryUnited States
CitySeattle, WA
Period07/11/1107/11/15

Keywords

  • Biomolecular recognition
  • Biosensor
  • In-situ real-time monitoring
  • Microcantilever
  • Resonator

ASJC Scopus subject areas

  • Engineering(all)
  • Mechanical Engineering

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