Nanomechanical microcantilever for In-Vitro biomolecular detection

Kilho Eom, Tae Yun Kwon, Jinsung Park, Sung Soo Na, Dae Sung Yoon, Tae Song Kim

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Nanomechanical microcantilevers have enabled the sensitive label-free detection of chemical and/or biological molecules. In recent years, resonating microcantilevers have achieved the unprecedented sensitivity in detecting molecules. In this article, we review our current works on the label-free detection of biomolecules based on resonating microcantilevers. Our piezoelectric thick film microcantilevers exhibit the relatively high quality factor in a viscous liquid, indicating the potential of our cantilever to in situ biosensor applications for real-time detection of biomolecular interactions. It is shown that our microcantilevers allow the noise-free real-time monitoring of biomolecular recognitions, providing the insight into kinetics of biomolecular recognitions.

Original languageEnglish
Title of host publicationASME International Mechanical Engineering Congress and Exposition, Proceedings
Pages821-842
Number of pages22
Volume10 PART B
DOIs
Publication statusPublished - 2008 May 30
EventASME International Mechanical Engineering Congress and Exposition, IMECE 2007 - Seattle, WA, United States
Duration: 2007 Nov 112007 Nov 15

Other

OtherASME International Mechanical Engineering Congress and Exposition, IMECE 2007
CountryUnited States
CitySeattle, WA
Period07/11/1107/11/15

Keywords

  • Biomolecular recognition
  • Biosensor
  • In-situ real-time monitoring
  • Microcantilever
  • Resonator

ASJC Scopus subject areas

  • Engineering(all)

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  • Cite this

    Eom, K., Kwon, T. Y., Park, J., Na, S. S., Yoon, D. S., & Kim, T. S. (2008). Nanomechanical microcantilever for In-Vitro biomolecular detection. In ASME International Mechanical Engineering Congress and Exposition, Proceedings (Vol. 10 PART B, pp. 821-842) https://doi.org/10.1115/IMECE2007-41290