Nanoparticle-based energy transfer for rapid and simple detection of protein glycosylation

Eunkeu Oh, Dohoon Lee, Young Pil Kim, Seung Youp Cha, Doo Byoung Oh, Hyun Ah Kang, Jungbae Kim, Hak Sung Kim

Research output: Contribution to journalArticle

69 Citations (Scopus)

Abstract

(Figure Presented) Photoluminescence quenching of dextranconjugated quantum dots (dex-QDs) by gold nanoparticles conjugated with concanavalin A (conA-AuNPs) can be prevented by adding a glycoprotein, which inhibits the association of dex-QDs with conA-AuNPs (see scheme). This phenomenon can be used as an analytical tool for the detection of protein glycosylation. PL = photoluminescence.

Original languageEnglish
Pages (from-to)7959-7963
Number of pages5
JournalAngewandte Chemie - International Edition
Volume45
Issue number47
DOIs
Publication statusPublished - 2006 Dec 4

Keywords

  • Carbohydrates
  • Energy transfer
  • Glycoproteins
  • Gold nanoparticles
  • Quantum dots

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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