Nanoparticle-based energy transfer for rapid and simple detection of protein glycosylation

Eunkeu Oh, Dohoon Lee, Young Pil Kim, Seung Youp Cha, Doo Beyong Oh, Hyun Ah Kang, Jungbae Kim, Hak Sung Kim

Research output: Contribution to journalArticle

68 Citations (Scopus)

Abstract

(Figure Presented) Photoluminescence quenching of dextranconjugated quantum dots (dex-QDs) by gold nanoparticles conjugated with concanavalin A (conA-AuNPs) can be prevented by adding a glycoprotein, which inhibits the association of dex-QDs with conA-AuNPs (see scheme). This phenomenon can be used as an analytical tool for the detection of protein glycosylation. PL = photoluminescence.

Original languageEnglish
Pages (from-to)7959-7963
Number of pages5
JournalAngewandte Chemie - International Edition
Volume45
Issue number47
DOIs
Publication statusPublished - 2006 Dec 4
Externally publishedYes

Fingerprint

Glycosylation
Energy transfer
Semiconductor quantum dots
Photoluminescence
Nanoparticles
Proteins
Glycoproteins
Concanavalin A
Gold
Quenching
Association reactions

Keywords

  • Carbohydrates
  • Energy transfer
  • Glycoproteins
  • Gold nanoparticles
  • Quantum dots

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Nanoparticle-based energy transfer for rapid and simple detection of protein glycosylation. / Oh, Eunkeu; Lee, Dohoon; Kim, Young Pil; Cha, Seung Youp; Oh, Doo Beyong; Kang, Hyun Ah; Kim, Jungbae; Kim, Hak Sung.

In: Angewandte Chemie - International Edition, Vol. 45, No. 47, 04.12.2006, p. 7959-7963.

Research output: Contribution to journalArticle

Oh, Eunkeu ; Lee, Dohoon ; Kim, Young Pil ; Cha, Seung Youp ; Oh, Doo Beyong ; Kang, Hyun Ah ; Kim, Jungbae ; Kim, Hak Sung. / Nanoparticle-based energy transfer for rapid and simple detection of protein glycosylation. In: Angewandte Chemie - International Edition. 2006 ; Vol. 45, No. 47. pp. 7959-7963.
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