Nanoprobes for optical bioimaging

Keunsoo Jeong, Youngsun Kim, Chi Soo Kang, Hong Jun Cho, Yong Deok Lee, Ick Chan Kwon, Sehoon Kim

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Imaging nanoprobes are a group of nano-sized contrast agents devised for providing improved contrast and spatial resolution for bioimaging. Among various imaging nanoprobes, optical nanoprobes capable of monitoring biological events or progresses in the cellular and molecular levels have been developed for early detection, accurate diagnosis, and personalized image-guided treatment of diseases. The optical activities of nanoprobes can be tuned on demand for specific applications by engineering their size, surface nature, morphology, and composition. In addition, by virtue of the nanostructure, nanoprobes have displayed favorable pharmacokinetic features and target specificity reflecting clinical demands. In this review, we focus on typical approaches and recent trends in development of nanoprobe-mediated optical imaging and their potential as a clinical diagnostic modality.

Original languageEnglish
Pages (from-to)1262-1279
Number of pages18
JournalOptical Materials Express
Volume6
Issue number4
DOIs
Publication statusPublished - 2016 Apr 1
Externally publishedYes

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ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials

Cite this

Jeong, K., Kim, Y., Kang, C. S., Cho, H. J., Lee, Y. D., Kwon, I. C., & Kim, S. (2016). Nanoprobes for optical bioimaging. Optical Materials Express, 6(4), 1262-1279. https://doi.org/10.1364/OME.6.001262