Nationwide survey of coronary aneurysms with diameter >6 mm in Kawasaki disease in Korea

Giyoung Jang, I. Seok Kang, Jae Young Choi, Eun Jung Bae, Young Hwue Kim, Seong Ho Kim, Jae Sook Ma

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background: We investigated the course of coronary aneurysm with diameter >6 mm in Kawasaki disease (KD), as well as related therapeutic trends and prognosis in Korea. Methods: A nationwide questionnaire survey was carried out in 77 hospitals, to investigate, retrospectively, patients with KD who had coronary aneurysms with a diameter >6 mm between 1990 and 2011. Results: The median age of onset was 3 years (range, 2 months-16 years) in a total of 239 patients. During the acute stage of KD, most patients received i.v. immunoglobulins and aspirin. In addition, 27 patients received steroid therapy. In the current study, the mean coronary aneurysm size was 8.7 ± 3.2 mm (range, 6-21 mm). Twenty-two patients underwent interventional catheterization. Procedures included percutaneous transluminal coronary balloon angioplasty (n = 10), stent placement (n = 9), and percutaneous transluminal coronary rotational ablation (n = 3). Fourteen patients underwent coronary artery bypass graft surgery. Of the 239 patients who had coronary aneurysms with diameter >6 mm, 13 (5.4%) presented with findings suggestive of myocardial infarction. Five patients died during the follow-up period. Conclusions: Severe stenosis or occlusion of the coronary artery may occur in some patients who develop coronary aneurysms with diameter >6 mm; early management such as coronary interventions or surgery should be considered in such cases.

Original languageEnglish
Pages (from-to)367-372
Number of pages6
JournalPediatrics International
Volume57
Issue number3
DOIs
Publication statusPublished - 2015 Jan 1

Fingerprint

Coronary Aneurysm
Mucocutaneous Lymph Node Syndrome
Korea
Surveys and Questionnaires
Coronary Balloon Angioplasty
Age of Onset
Coronary Artery Bypass
Catheterization
Aspirin
Stents
Immunoglobulins
Coronary Vessels
Pathologic Constriction
Steroids
Myocardial Infarction
Transplants

Keywords

  • complication
  • coronary aneurysm
  • Kawasaki disease
  • prognosis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Jang, G., Kang, I. S., Choi, J. Y., Bae, E. J., Kim, Y. H., Kim, S. H., & Ma, J. S. (2015). Nationwide survey of coronary aneurysms with diameter >6 mm in Kawasaki disease in Korea. Pediatrics International, 57(3), 367-372. https://doi.org/10.1111/ped.12536

Nationwide survey of coronary aneurysms with diameter >6 mm in Kawasaki disease in Korea. / Jang, Giyoung; Kang, I. Seok; Choi, Jae Young; Bae, Eun Jung; Kim, Young Hwue; Kim, Seong Ho; Ma, Jae Sook.

In: Pediatrics International, Vol. 57, No. 3, 01.01.2015, p. 367-372.

Research output: Contribution to journalArticle

Jang, Giyoung ; Kang, I. Seok ; Choi, Jae Young ; Bae, Eun Jung ; Kim, Young Hwue ; Kim, Seong Ho ; Ma, Jae Sook. / Nationwide survey of coronary aneurysms with diameter >6 mm in Kawasaki disease in Korea. In: Pediatrics International. 2015 ; Vol. 57, No. 3. pp. 367-372.
@article{8294b5f9f08b4627a95a9a268e9dac75,
title = "Nationwide survey of coronary aneurysms with diameter >6 mm in Kawasaki disease in Korea",
abstract = "Background: We investigated the course of coronary aneurysm with diameter >6 mm in Kawasaki disease (KD), as well as related therapeutic trends and prognosis in Korea. Methods: A nationwide questionnaire survey was carried out in 77 hospitals, to investigate, retrospectively, patients with KD who had coronary aneurysms with a diameter >6 mm between 1990 and 2011. Results: The median age of onset was 3 years (range, 2 months-16 years) in a total of 239 patients. During the acute stage of KD, most patients received i.v. immunoglobulins and aspirin. In addition, 27 patients received steroid therapy. In the current study, the mean coronary aneurysm size was 8.7 ± 3.2 mm (range, 6-21 mm). Twenty-two patients underwent interventional catheterization. Procedures included percutaneous transluminal coronary balloon angioplasty (n = 10), stent placement (n = 9), and percutaneous transluminal coronary rotational ablation (n = 3). Fourteen patients underwent coronary artery bypass graft surgery. Of the 239 patients who had coronary aneurysms with diameter >6 mm, 13 (5.4{\%}) presented with findings suggestive of myocardial infarction. Five patients died during the follow-up period. Conclusions: Severe stenosis or occlusion of the coronary artery may occur in some patients who develop coronary aneurysms with diameter >6 mm; early management such as coronary interventions or surgery should be considered in such cases.",
keywords = "complication, coronary aneurysm, Kawasaki disease, prognosis",
author = "Giyoung Jang and Kang, {I. Seok} and Choi, {Jae Young} and Bae, {Eun Jung} and Kim, {Young Hwue} and Kim, {Seong Ho} and Ma, {Jae Sook}",
year = "2015",
month = "1",
day = "1",
doi = "10.1111/ped.12536",
language = "English",
volume = "57",
pages = "367--372",
journal = "Pediatrics International",
issn = "1328-8067",
publisher = "Wiley-Blackwell",
number = "3",

}

TY - JOUR

T1 - Nationwide survey of coronary aneurysms with diameter >6 mm in Kawasaki disease in Korea

AU - Jang, Giyoung

AU - Kang, I. Seok

AU - Choi, Jae Young

AU - Bae, Eun Jung

AU - Kim, Young Hwue

AU - Kim, Seong Ho

AU - Ma, Jae Sook

PY - 2015/1/1

Y1 - 2015/1/1

N2 - Background: We investigated the course of coronary aneurysm with diameter >6 mm in Kawasaki disease (KD), as well as related therapeutic trends and prognosis in Korea. Methods: A nationwide questionnaire survey was carried out in 77 hospitals, to investigate, retrospectively, patients with KD who had coronary aneurysms with a diameter >6 mm between 1990 and 2011. Results: The median age of onset was 3 years (range, 2 months-16 years) in a total of 239 patients. During the acute stage of KD, most patients received i.v. immunoglobulins and aspirin. In addition, 27 patients received steroid therapy. In the current study, the mean coronary aneurysm size was 8.7 ± 3.2 mm (range, 6-21 mm). Twenty-two patients underwent interventional catheterization. Procedures included percutaneous transluminal coronary balloon angioplasty (n = 10), stent placement (n = 9), and percutaneous transluminal coronary rotational ablation (n = 3). Fourteen patients underwent coronary artery bypass graft surgery. Of the 239 patients who had coronary aneurysms with diameter >6 mm, 13 (5.4%) presented with findings suggestive of myocardial infarction. Five patients died during the follow-up period. Conclusions: Severe stenosis or occlusion of the coronary artery may occur in some patients who develop coronary aneurysms with diameter >6 mm; early management such as coronary interventions or surgery should be considered in such cases.

AB - Background: We investigated the course of coronary aneurysm with diameter >6 mm in Kawasaki disease (KD), as well as related therapeutic trends and prognosis in Korea. Methods: A nationwide questionnaire survey was carried out in 77 hospitals, to investigate, retrospectively, patients with KD who had coronary aneurysms with a diameter >6 mm between 1990 and 2011. Results: The median age of onset was 3 years (range, 2 months-16 years) in a total of 239 patients. During the acute stage of KD, most patients received i.v. immunoglobulins and aspirin. In addition, 27 patients received steroid therapy. In the current study, the mean coronary aneurysm size was 8.7 ± 3.2 mm (range, 6-21 mm). Twenty-two patients underwent interventional catheterization. Procedures included percutaneous transluminal coronary balloon angioplasty (n = 10), stent placement (n = 9), and percutaneous transluminal coronary rotational ablation (n = 3). Fourteen patients underwent coronary artery bypass graft surgery. Of the 239 patients who had coronary aneurysms with diameter >6 mm, 13 (5.4%) presented with findings suggestive of myocardial infarction. Five patients died during the follow-up period. Conclusions: Severe stenosis or occlusion of the coronary artery may occur in some patients who develop coronary aneurysms with diameter >6 mm; early management such as coronary interventions or surgery should be considered in such cases.

KW - complication

KW - coronary aneurysm

KW - Kawasaki disease

KW - prognosis

UR - http://www.scopus.com/inward/record.url?scp=84933500956&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84933500956&partnerID=8YFLogxK

U2 - 10.1111/ped.12536

DO - 10.1111/ped.12536

M3 - Article

VL - 57

SP - 367

EP - 372

JO - Pediatrics International

JF - Pediatrics International

SN - 1328-8067

IS - 3

ER -