Neonatal invasive Streptococcus gallolyticus subsp. pasteurianus infection with delayed central nervous system complications

Jung Weon Park, So-Hee Eun, Eui Chong Kim, Moon Woo Seong, Yun Kyung Kim

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Group D streptococci are known to cause newborn septicemia and meningitis, but the Streptococcus bovis group strains rarely cause serious neonatal infections in Korea. Central nervous system (CNS) complications of neonatal S. bovis group infection have rarely been reported. In adults, S. bovis group strains cause bacteremia and endocarditis, and are associated with gastrointestinal malignancy. However, only a few studies have reported meningitis and septicemia in infants. Here, we describe a case of bacteremia and meningitis due to Streptococcus gallolyticus subsp. pasteurianus with a delayed CNS complication in an infant. A 28-day-old male infant was admitted to the hospital with a 1-day history of fever. Cultures of blood, cerebrospinal fluid, and urine showed the presence of S. bovis group strain—S. gallolyticus subsp. pasteurianus. He was discharged after 21 days of intravenous ampicillin and cefotaxime administration. Two weeks later, he was readmitted with a fever and short episodes of tonic-clonic movements. Brain magnetic resonance imaging showed marked bilateral frontal subdural effusion. He was discharged after 31 days of antibiotic therapy, and no neurological sequelae were observed at the 9-month follow-up. In conclusion, we present a rare case of neonatal S. gallolyticus subsp. pasteurianus infection causing urinary tract infection, septicemia, meningitis, and delayed CNS complications. This case emphasizes the need for physicians to be aware of S. bovis infection in infants.

Original languageEnglish
Pages (from-to)33-36
Number of pages4
JournalKorean Journal of Pediatrics
Volume58
Issue number1
DOIs
Publication statusPublished - 2015 Jan 1

Fingerprint

Streptococcus bovis
Meningitis
Central Nervous System
Infection
Sepsis
Bacteremia
Fever
Subdural Effusion
Cefotaxime
Enterococcus faecalis
Ampicillin
Korea
Endocarditis
Urinary Tract Infections
Cerebrospinal Fluid
Magnetic Resonance Imaging
Streptococcus gallolyticus
Urine
Newborn Infant
Anti-Bacterial Agents

Keywords

  • Bacteremia
  • Infant
  • Sepsis
  • Streptococcal infection
  • Streptococcus bovis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pediatrics

Cite this

Neonatal invasive Streptococcus gallolyticus subsp. pasteurianus infection with delayed central nervous system complications. / Park, Jung Weon; Eun, So-Hee; Kim, Eui Chong; Seong, Moon Woo; Kim, Yun Kyung.

In: Korean Journal of Pediatrics, Vol. 58, No. 1, 01.01.2015, p. 33-36.

Research output: Contribution to journalArticle

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