Neurocognitive function and quality of life in relation to hematocrit levels in chronic hemodialysis patients

Sun Young Lee, Heon Jeong Lee, Yong Ku Kim, Seung Hyun Kim, Leen Kim, Min Soo Lee, Sook Haeng Joe, In Kwa Jung, Kwang Yoon Suh, Hyung Kyu Kim

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Objective: We examined the putative association between the levels of hematocrit and improvement of cognitive function as well as quality of life in patients with end-stage renal disease (ESRD). Methods: Fifty-six ESRD patients were divided into two groups according to their hematocrit levels: Group A consisted of 28 patients with hematocrit levels lower than the median (27.2 g%), while Group B, the remaining 28 patients, with higher than the median level. Neurocognitive function and the quality of life in these two groups were compared. Results: Although patients with higher hematocrit levels scored better in the neurocognitive function tests such as the forward digit-span (P=.034) and digit-symbol (P=.023), their quality of life evaluated by three scales (Karnofsky Scale, Index of Well-Being, and SF-36) was not any better than those with lower hematocrit group. Conclusions: The present study indicated that in chronic hemodialysis patients, the higher hematocrit levels improve neurocognitive function but not the quality of life.

Original languageEnglish
Pages (from-to)5-10
Number of pages6
JournalJournal of Psychosomatic Research
Volume57
Issue number1
DOIs
Publication statusPublished - 2004 Jul

Keywords

  • Hematocrit
  • Hemodialysis
  • Neurocognitive function
  • Quality of life

ASJC Scopus subject areas

  • Clinical Psychology
  • Psychiatry and Mental health

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