Neurocognitive function and quality of life in relation to hematocrit levels in chronic hemodialysis patients

Sun Young Lee, Heon-Jeong Lee, Yong Ku Kim, Seung Hyun Kim, Leen Kim, Min-Soo Lee, Sook Haeng Joe, In Kwa Jung, Kwang Yoon Suh, Hyung Kyu Kim

Research output: Contribution to journalArticle

23 Citations (Scopus)


Objective: We examined the putative association between the levels of hematocrit and improvement of cognitive function as well as quality of life in patients with end-stage renal disease (ESRD). Methods: Fifty-six ESRD patients were divided into two groups according to their hematocrit levels: Group A consisted of 28 patients with hematocrit levels lower than the median (27.2 g%), while Group B, the remaining 28 patients, with higher than the median level. Neurocognitive function and the quality of life in these two groups were compared. Results: Although patients with higher hematocrit levels scored better in the neurocognitive function tests such as the forward digit-span (P=.034) and digit-symbol (P=.023), their quality of life evaluated by three scales (Karnofsky Scale, Index of Well-Being, and SF-36) was not any better than those with lower hematocrit group. Conclusions: The present study indicated that in chronic hemodialysis patients, the higher hematocrit levels improve neurocognitive function but not the quality of life.

Original languageEnglish
Pages (from-to)5-10
Number of pages6
JournalJournal of Psychosomatic Research
Issue number1
Publication statusPublished - 2004 Jul 1


  • Hematocrit
  • Hemodialysis
  • Neurocognitive function
  • Quality of life

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry
  • Psychology(all)

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