Neurocognitive function and quality of life in relation to hematocrit levels in chronic hemodialysis patients

Sun Young Lee, Heon-Jeong Lee, Yong Ku Kim, Seung Hyun Kim, Leen Kim, Min-Soo Lee, Sook Haeng Joe, In Kwa Jung, Kwang Yoon Suh, Hyung Kyu Kim

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Objective: We examined the putative association between the levels of hematocrit and improvement of cognitive function as well as quality of life in patients with end-stage renal disease (ESRD). Methods: Fifty-six ESRD patients were divided into two groups according to their hematocrit levels: Group A consisted of 28 patients with hematocrit levels lower than the median (27.2 g%), while Group B, the remaining 28 patients, with higher than the median level. Neurocognitive function and the quality of life in these two groups were compared. Results: Although patients with higher hematocrit levels scored better in the neurocognitive function tests such as the forward digit-span (P=.034) and digit-symbol (P=.023), their quality of life evaluated by three scales (Karnofsky Scale, Index of Well-Being, and SF-36) was not any better than those with lower hematocrit group. Conclusions: The present study indicated that in chronic hemodialysis patients, the higher hematocrit levels improve neurocognitive function but not the quality of life.

Original languageEnglish
Pages (from-to)5-10
Number of pages6
JournalJournal of Psychosomatic Research
Volume57
Issue number1
DOIs
Publication statusPublished - 2004 Jul 1

Fingerprint

Hematocrit
Renal Dialysis
Quality of Life
Karnofsky Performance Status
Chronic Kidney Failure
Cognition

Keywords

  • Hematocrit
  • Hemodialysis
  • Neurocognitive function
  • Quality of life

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry
  • Psychology(all)

Cite this

Neurocognitive function and quality of life in relation to hematocrit levels in chronic hemodialysis patients. / Lee, Sun Young; Lee, Heon-Jeong; Kim, Yong Ku; Kim, Seung Hyun; Kim, Leen; Lee, Min-Soo; Joe, Sook Haeng; Jung, In Kwa; Suh, Kwang Yoon; Kim, Hyung Kyu.

In: Journal of Psychosomatic Research, Vol. 57, No. 1, 01.07.2004, p. 5-10.

Research output: Contribution to journalArticle

Lee, Sun Young ; Lee, Heon-Jeong ; Kim, Yong Ku ; Kim, Seung Hyun ; Kim, Leen ; Lee, Min-Soo ; Joe, Sook Haeng ; Jung, In Kwa ; Suh, Kwang Yoon ; Kim, Hyung Kyu. / Neurocognitive function and quality of life in relation to hematocrit levels in chronic hemodialysis patients. In: Journal of Psychosomatic Research. 2004 ; Vol. 57, No. 1. pp. 5-10.
@article{13b9250cd7e84d32aab5cb01d6032aea,
title = "Neurocognitive function and quality of life in relation to hematocrit levels in chronic hemodialysis patients",
abstract = "Objective: We examined the putative association between the levels of hematocrit and improvement of cognitive function as well as quality of life in patients with end-stage renal disease (ESRD). Methods: Fifty-six ESRD patients were divided into two groups according to their hematocrit levels: Group A consisted of 28 patients with hematocrit levels lower than the median (27.2 g{\%}), while Group B, the remaining 28 patients, with higher than the median level. Neurocognitive function and the quality of life in these two groups were compared. Results: Although patients with higher hematocrit levels scored better in the neurocognitive function tests such as the forward digit-span (P=.034) and digit-symbol (P=.023), their quality of life evaluated by three scales (Karnofsky Scale, Index of Well-Being, and SF-36) was not any better than those with lower hematocrit group. Conclusions: The present study indicated that in chronic hemodialysis patients, the higher hematocrit levels improve neurocognitive function but not the quality of life.",
keywords = "Hematocrit, Hemodialysis, Neurocognitive function, Quality of life",
author = "Lee, {Sun Young} and Heon-Jeong Lee and Kim, {Yong Ku} and Kim, {Seung Hyun} and Leen Kim and Min-Soo Lee and Joe, {Sook Haeng} and Jung, {In Kwa} and Suh, {Kwang Yoon} and Kim, {Hyung Kyu}",
year = "2004",
month = "7",
day = "1",
doi = "10.1016/S0022-3999(03)00528-2",
language = "English",
volume = "57",
pages = "5--10",
journal = "Journal of Psychosomatic Research",
issn = "0022-3999",
publisher = "Elsevier Inc.",
number = "1",

}

TY - JOUR

T1 - Neurocognitive function and quality of life in relation to hematocrit levels in chronic hemodialysis patients

AU - Lee, Sun Young

AU - Lee, Heon-Jeong

AU - Kim, Yong Ku

AU - Kim, Seung Hyun

AU - Kim, Leen

AU - Lee, Min-Soo

AU - Joe, Sook Haeng

AU - Jung, In Kwa

AU - Suh, Kwang Yoon

AU - Kim, Hyung Kyu

PY - 2004/7/1

Y1 - 2004/7/1

N2 - Objective: We examined the putative association between the levels of hematocrit and improvement of cognitive function as well as quality of life in patients with end-stage renal disease (ESRD). Methods: Fifty-six ESRD patients were divided into two groups according to their hematocrit levels: Group A consisted of 28 patients with hematocrit levels lower than the median (27.2 g%), while Group B, the remaining 28 patients, with higher than the median level. Neurocognitive function and the quality of life in these two groups were compared. Results: Although patients with higher hematocrit levels scored better in the neurocognitive function tests such as the forward digit-span (P=.034) and digit-symbol (P=.023), their quality of life evaluated by three scales (Karnofsky Scale, Index of Well-Being, and SF-36) was not any better than those with lower hematocrit group. Conclusions: The present study indicated that in chronic hemodialysis patients, the higher hematocrit levels improve neurocognitive function but not the quality of life.

AB - Objective: We examined the putative association between the levels of hematocrit and improvement of cognitive function as well as quality of life in patients with end-stage renal disease (ESRD). Methods: Fifty-six ESRD patients were divided into two groups according to their hematocrit levels: Group A consisted of 28 patients with hematocrit levels lower than the median (27.2 g%), while Group B, the remaining 28 patients, with higher than the median level. Neurocognitive function and the quality of life in these two groups were compared. Results: Although patients with higher hematocrit levels scored better in the neurocognitive function tests such as the forward digit-span (P=.034) and digit-symbol (P=.023), their quality of life evaluated by three scales (Karnofsky Scale, Index of Well-Being, and SF-36) was not any better than those with lower hematocrit group. Conclusions: The present study indicated that in chronic hemodialysis patients, the higher hematocrit levels improve neurocognitive function but not the quality of life.

KW - Hematocrit

KW - Hemodialysis

KW - Neurocognitive function

KW - Quality of life

UR - http://www.scopus.com/inward/record.url?scp=3142600581&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=3142600581&partnerID=8YFLogxK

U2 - 10.1016/S0022-3999(03)00528-2

DO - 10.1016/S0022-3999(03)00528-2

M3 - Article

VL - 57

SP - 5

EP - 10

JO - Journal of Psychosomatic Research

JF - Journal of Psychosomatic Research

SN - 0022-3999

IS - 1

ER -