Neuropathic pain components in patients with lumbar spinal stenosis

Si Young Park, Howard S. An, Seong Hwan Moon, Hwan Mo Lee, Seung-Woo Suh, Ding Chen, Jin Ho Jeon

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Purpose: To determine the prevalence and characteristics of neuropathic pain (NP) in patients with lumbar spinal stenosis (LSS) according to subgroup analysis of symptoms. Materials and Methods: We prospectively enrolled subjects with LSS (n=86) who were scheduled to undergo spinal surgery. The patients were divided into two groups according to a chief complaint of radicular pain or neurogenic claudication. We measured patient’s pain score using the visual analog scale (VAS), Oswestry Disability Index (ODI) and Leads Assessment of Neuropathic Symptoms and Signs (LANSS). According to LANSS value, the prevalence of NP component pain in patients with LSS was assessed. Statistical analysis was performed to find the relationship between LANSS scores and the other scores. Results: From our sample of 86 patients, 31 (36.0%) had a NP component, with 24 (63.4%) in the radicular pain group having NP. However, only seven patients (15.6%) in the neurogenic claudication group had NP. The LANSS pain score was not significantly correlated with VAS scores for back pain, but did correlate with VAS scores for leg pain (R=0.73, p<0.001) and with ODI back pain scores (R=0.54, p<0.01). Conclusion: One-third of the patients with LSS had a NP component. The presence of radicular pain correlated strongly with NP. The severity of leg pain and ODI score were also closely related to a NP component. This data may prove useful to understanding the pain characteristics of LSS and in better designing clinical trials for NP treatment in patients with LSS.

Original languageEnglish
Pages (from-to)1044-1050
Number of pages7
JournalYonsei Medical Journal
Volume56
Issue number4
DOIs
Publication statusPublished - 2015 Jul 1

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Spinal Stenosis
Neuralgia
Pain
Symptom Assessment
Signs and Symptoms
Visual Analog Scale
Back Pain
Leg
Clinical Trials

Keywords

  • Leads assessment of neuropathic symptoms and signs
  • Neuropathic pain
  • Oswestry disability index
  • Spinal stenosis
  • Visual analog scale

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Neuropathic pain components in patients with lumbar spinal stenosis. / Park, Si Young; An, Howard S.; Moon, Seong Hwan; Lee, Hwan Mo; Suh, Seung-Woo; Chen, Ding; Jeon, Jin Ho.

In: Yonsei Medical Journal, Vol. 56, No. 4, 01.07.2015, p. 1044-1050.

Research output: Contribution to journalArticle

Park, Si Young ; An, Howard S. ; Moon, Seong Hwan ; Lee, Hwan Mo ; Suh, Seung-Woo ; Chen, Ding ; Jeon, Jin Ho. / Neuropathic pain components in patients with lumbar spinal stenosis. In: Yonsei Medical Journal. 2015 ; Vol. 56, No. 4. pp. 1044-1050.
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abstract = "Purpose: To determine the prevalence and characteristics of neuropathic pain (NP) in patients with lumbar spinal stenosis (LSS) according to subgroup analysis of symptoms. Materials and Methods: We prospectively enrolled subjects with LSS (n=86) who were scheduled to undergo spinal surgery. The patients were divided into two groups according to a chief complaint of radicular pain or neurogenic claudication. We measured patient’s pain score using the visual analog scale (VAS), Oswestry Disability Index (ODI) and Leads Assessment of Neuropathic Symptoms and Signs (LANSS). According to LANSS value, the prevalence of NP component pain in patients with LSS was assessed. Statistical analysis was performed to find the relationship between LANSS scores and the other scores. Results: From our sample of 86 patients, 31 (36.0{\%}) had a NP component, with 24 (63.4{\%}) in the radicular pain group having NP. However, only seven patients (15.6{\%}) in the neurogenic claudication group had NP. The LANSS pain score was not significantly correlated with VAS scores for back pain, but did correlate with VAS scores for leg pain (R=0.73, p<0.001) and with ODI back pain scores (R=0.54, p<0.01). Conclusion: One-third of the patients with LSS had a NP component. The presence of radicular pain correlated strongly with NP. The severity of leg pain and ODI score were also closely related to a NP component. This data may prove useful to understanding the pain characteristics of LSS and in better designing clinical trials for NP treatment in patients with LSS.",
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