New fabrication methods of bioactive and biodegradable scaffolds for bone tissue engineering

Youngmee Jung, Su Hee Kim, Sang Heon Kim, Soo Hyun Kim

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Bioceramic and polymers have been used as matrices for bone tissue engineering, and successful bone regeneration depends on cellular interaction with these matrices. The aim of this study was to fabricate polymer/ceramics composites with a novel sintering method. Also, we prepared homogenous porous poly(lactide-co-glycolide (PLGA) scaffolds in the supercritical CO2. These scaffolds had homogenous porous structure and high tensile and compressive mechanical properties compared to the scaffold prepared by conventional solvent casting method. This study revealed that generating bioactive and porous polymer scaffolds with novel sintering method or supercritical fluid technique could be useful for bone tissue engineering.

Original languageEnglish
Pages (from-to)261-270
Number of pages10
JournalJournal of Cellular Plastics
Volume47
Issue number3
DOIs
Publication statusPublished - 2011 May 1
Externally publishedYes

Keywords

  • composite scaffold
  • novel sintering
  • poly(lactide-co-glycolide)
  • supercritical fluid

ASJC Scopus subject areas

  • Materials Chemistry
  • Polymers and Plastics
  • Chemistry(all)

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