New multi-task learning model to predict Alzheimer’s disease cognitive assessment

Zhouyuan Huo, Dinggang Shen, Heng Huang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Citations (Scopus)

Abstract

As a neurodegenerative disorder,the Alzheimer’s disease (AD) status can be characterized by the progressive impairment of memory and other cognitive functions. Thus,it is an important topic to use neuroimaging measures to predict cognitive performance and track the progression of AD. Many existing cognitive performance prediction methods employ the regression models to associate cognitive scores to neuroimaging measures,but these methods do not take into account the interconnected structures within imaging data and those among cognitive scores. To address this problem,we propose a novel multi-task learning model for minimizing the k smallest singular values to uncover the underlying low-rank common subspace and jointly analyze all the imaging and clinical data. The effectiveness of our method is demonstrated by the clearly improved prediction performances in all empirical AD cognitive scores prediction cases.

Original languageEnglish
Title of host publicationMedical Image Computing and Computer-Assisted Intervention - MICCAI 2016 - 19th International Conference, Proceedings
PublisherSpringer Verlag
Pages317-325
Number of pages9
Volume9900 LNCS
ISBN (Print)9783319467191
DOIs
Publication statusPublished - 2016
Externally publishedYes
Event1st International Workshop on Simulation and Synthesis in Medical Imaging, SASHIMI 2016 held in conjunction with 19th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2016 - Athens, Greece
Duration: 2016 Oct 212016 Oct 21

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume9900 LNCS
ISSN (Print)03029743
ISSN (Electronic)16113349

Other

Other1st International Workshop on Simulation and Synthesis in Medical Imaging, SASHIMI 2016 held in conjunction with 19th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2016
CountryGreece
CityAthens
Period16/10/2116/10/21

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)

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  • Cite this

    Huo, Z., Shen, D., & Huang, H. (2016). New multi-task learning model to predict Alzheimer’s disease cognitive assessment. In Medical Image Computing and Computer-Assisted Intervention - MICCAI 2016 - 19th International Conference, Proceedings (Vol. 9900 LNCS, pp. 317-325). (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 9900 LNCS). Springer Verlag. https://doi.org/10.1007/978-3-319-46720-7_37