Abstract
Purpose: To evaluate radiological findings of non-calcified ductal carcinoma in situ (DCIS) and to correlate those with histological features. Materials and Methods: From July 2002 to March 2006, 22 patients with histologically-proven non-calcified DCIS were included. Mammography was obtained in 19 patients, ultrasound in 18 patients, and both examinations in 15 patients. Radiological findings were evaluated according to the Breast Imaging Reporting and Data System by American College of Radiology. Histological tumor subtype and Van Nuys classification of DCIS were assessed. Results: Histological subtypes consisted of mixed type in 11 patients (50%), comedo in 4 (18%), cribriform in 4 (18%), papillary type in 2 (9%), and solid in one (5%). According to Van Nuys classification, group 3 DCIS was observed in 13 (59%) patients. In the 19 patients who underwent mammography, 13 patients presented with abnormal findings: focal asymmetry in 7 patients (37%), masses in 4 (21%), skin thickening in one (5%), and architectural distortion in one (5%). In the 18 patients who had received breast ultrasound, a mass was present in 15 (83%) patients and ductal changes in 3 patients (17%). Sixty percent of patients with masses on ultrasound had group 3 DCIS and 100% of patients with ductal change had group 1 DCIS (p= 0.017). Conclusion: Diagnosis of non-calcified DCIS by mammography is not an easy task due to the lack of typical malignant calcifications or masses. High resolution ultrasound can be useful for detecting non-calcified DCIS, and ultrasound findings are correlated with histological features.
| Original language | English |
|---|---|
| Pages (from-to) | 103-110 |
| Number of pages | 8 |
| Journal | Yonsei Medical Journal |
| Volume | 49 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2008 Feb 1 |
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Keywords
- Breast neoplams
- Mammary ultrasonography
- Mammography
- Noninfiltrating intraductal carcinoma
ASJC Scopus subject areas
- Medicine(all)
Cite this
Non-calcified ductal carcinoma in situ : Ultrasound and mammographic findings correlated with histological findings. / Cho, Kyu Ran; Seo, Bo Kyoung; Kim, Chul Hwan; Whang, Kyu Won; Kim, Yun Hwan; Kim, Baek Hyun; Woo, Ok Hee; Lee, Young Hen; Chung, Kyoo Byung.
In: Yonsei Medical Journal, Vol. 49, No. 1, 01.02.2008, p. 103-110.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Non-calcified ductal carcinoma in situ
T2 - Ultrasound and mammographic findings correlated with histological findings
AU - Cho, Kyu Ran
AU - Seo, Bo Kyoung
AU - Kim, Chul Hwan
AU - Whang, Kyu Won
AU - Kim, Yun Hwan
AU - Kim, Baek Hyun
AU - Woo, Ok Hee
AU - Lee, Young Hen
AU - Chung, Kyoo Byung
PY - 2008/2/1
Y1 - 2008/2/1
N2 - Purpose: To evaluate radiological findings of non-calcified ductal carcinoma in situ (DCIS) and to correlate those with histological features. Materials and Methods: From July 2002 to March 2006, 22 patients with histologically-proven non-calcified DCIS were included. Mammography was obtained in 19 patients, ultrasound in 18 patients, and both examinations in 15 patients. Radiological findings were evaluated according to the Breast Imaging Reporting and Data System by American College of Radiology. Histological tumor subtype and Van Nuys classification of DCIS were assessed. Results: Histological subtypes consisted of mixed type in 11 patients (50%), comedo in 4 (18%), cribriform in 4 (18%), papillary type in 2 (9%), and solid in one (5%). According to Van Nuys classification, group 3 DCIS was observed in 13 (59%) patients. In the 19 patients who underwent mammography, 13 patients presented with abnormal findings: focal asymmetry in 7 patients (37%), masses in 4 (21%), skin thickening in one (5%), and architectural distortion in one (5%). In the 18 patients who had received breast ultrasound, a mass was present in 15 (83%) patients and ductal changes in 3 patients (17%). Sixty percent of patients with masses on ultrasound had group 3 DCIS and 100% of patients with ductal change had group 1 DCIS (p= 0.017). Conclusion: Diagnosis of non-calcified DCIS by mammography is not an easy task due to the lack of typical malignant calcifications or masses. High resolution ultrasound can be useful for detecting non-calcified DCIS, and ultrasound findings are correlated with histological features.
AB - Purpose: To evaluate radiological findings of non-calcified ductal carcinoma in situ (DCIS) and to correlate those with histological features. Materials and Methods: From July 2002 to March 2006, 22 patients with histologically-proven non-calcified DCIS were included. Mammography was obtained in 19 patients, ultrasound in 18 patients, and both examinations in 15 patients. Radiological findings were evaluated according to the Breast Imaging Reporting and Data System by American College of Radiology. Histological tumor subtype and Van Nuys classification of DCIS were assessed. Results: Histological subtypes consisted of mixed type in 11 patients (50%), comedo in 4 (18%), cribriform in 4 (18%), papillary type in 2 (9%), and solid in one (5%). According to Van Nuys classification, group 3 DCIS was observed in 13 (59%) patients. In the 19 patients who underwent mammography, 13 patients presented with abnormal findings: focal asymmetry in 7 patients (37%), masses in 4 (21%), skin thickening in one (5%), and architectural distortion in one (5%). In the 18 patients who had received breast ultrasound, a mass was present in 15 (83%) patients and ductal changes in 3 patients (17%). Sixty percent of patients with masses on ultrasound had group 3 DCIS and 100% of patients with ductal change had group 1 DCIS (p= 0.017). Conclusion: Diagnosis of non-calcified DCIS by mammography is not an easy task due to the lack of typical malignant calcifications or masses. High resolution ultrasound can be useful for detecting non-calcified DCIS, and ultrasound findings are correlated with histological features.
KW - Breast neoplams
KW - Mammary ultrasonography
KW - Mammography
KW - Noninfiltrating intraductal carcinoma
UR - http://www.scopus.com/inward/record.url?scp=41949119999&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=41949119999&partnerID=8YFLogxK
U2 - 10.3349/ymj.2008.49.1.103
DO - 10.3349/ymj.2008.49.1.103
M3 - Article
C2 - 18306476
AN - SCOPUS:41949119999
VL - 49
SP - 103
EP - 110
JO - Yonsei Medical Journal
JF - Yonsei Medical Journal
SN - 0513-5796
IS - 1
ER -