Non-lithographic wrinkle nanochannels for protein preconcentration

Seok Chung, Jeong Hoon Lee, Myoung Woon Moon, Jongyoon Han, Roger D. Kamm

Research output: Contribution to journalArticle

99 Citations (Scopus)

Abstract

A low-cost fabrication method is proposed for preparing close-packed nanofluidic channels for protein pre-concentration. The wrinkle pattern can be prepared by stretching a sheet of poly(dimethyl siloxane) (PDMS) and treating with oxygen plasma to produce stiff skin. The study applied strain to a PDMS sheet and then applied plasma treatment to the sheet. A strain directly applied on the PDMS layer with microfluidic channels during the study to produce inhomogeneous nanofluidic channels, the channels has three sides made of PDMS and one side made from glass. It was observed during the study that the WNCs can be integrated with microfluidic channels that further produce a functional and uniform nanochannel array. The study also found that the WNCs can produce uniform array of high density with controlled dimensions in a specified region.

Original languageEnglish
Pages (from-to)3011-3016
Number of pages6
JournalAdvanced Materials
Volume20
Issue number16
DOIs
Publication statusPublished - 2008 Aug 18
Externally publishedYes

Fingerprint

Nanofluidics
Siloxanes
Microfluidics
Proteins
Plasmas
Stretching
Skin
Fabrication
Glass
Oxygen
Costs

ASJC Scopus subject areas

  • Mechanical Engineering
  • Mechanics of Materials
  • Materials Science(all)

Cite this

Non-lithographic wrinkle nanochannels for protein preconcentration. / Chung, Seok; Lee, Jeong Hoon; Moon, Myoung Woon; Han, Jongyoon; Kamm, Roger D.

In: Advanced Materials, Vol. 20, No. 16, 18.08.2008, p. 3011-3016.

Research output: Contribution to journalArticle

Chung, Seok ; Lee, Jeong Hoon ; Moon, Myoung Woon ; Han, Jongyoon ; Kamm, Roger D. / Non-lithographic wrinkle nanochannels for protein preconcentration. In: Advanced Materials. 2008 ; Vol. 20, No. 16. pp. 3011-3016.
@article{76885f57cefa4065860ef2c90aeaf778,
title = "Non-lithographic wrinkle nanochannels for protein preconcentration",
abstract = "A low-cost fabrication method is proposed for preparing close-packed nanofluidic channels for protein pre-concentration. The wrinkle pattern can be prepared by stretching a sheet of poly(dimethyl siloxane) (PDMS) and treating with oxygen plasma to produce stiff skin. The study applied strain to a PDMS sheet and then applied plasma treatment to the sheet. A strain directly applied on the PDMS layer with microfluidic channels during the study to produce inhomogeneous nanofluidic channels, the channels has three sides made of PDMS and one side made from glass. It was observed during the study that the WNCs can be integrated with microfluidic channels that further produce a functional and uniform nanochannel array. The study also found that the WNCs can produce uniform array of high density with controlled dimensions in a specified region.",
author = "Seok Chung and Lee, {Jeong Hoon} and Moon, {Myoung Woon} and Jongyoon Han and Kamm, {Roger D.}",
year = "2008",
month = "8",
day = "18",
doi = "10.1002/adma.200701715",
language = "English",
volume = "20",
pages = "3011--3016",
journal = "Advanced Materials",
issn = "0935-9648",
publisher = "Wiley-VCH Verlag",
number = "16",

}

TY - JOUR

T1 - Non-lithographic wrinkle nanochannels for protein preconcentration

AU - Chung, Seok

AU - Lee, Jeong Hoon

AU - Moon, Myoung Woon

AU - Han, Jongyoon

AU - Kamm, Roger D.

PY - 2008/8/18

Y1 - 2008/8/18

N2 - A low-cost fabrication method is proposed for preparing close-packed nanofluidic channels for protein pre-concentration. The wrinkle pattern can be prepared by stretching a sheet of poly(dimethyl siloxane) (PDMS) and treating with oxygen plasma to produce stiff skin. The study applied strain to a PDMS sheet and then applied plasma treatment to the sheet. A strain directly applied on the PDMS layer with microfluidic channels during the study to produce inhomogeneous nanofluidic channels, the channels has three sides made of PDMS and one side made from glass. It was observed during the study that the WNCs can be integrated with microfluidic channels that further produce a functional and uniform nanochannel array. The study also found that the WNCs can produce uniform array of high density with controlled dimensions in a specified region.

AB - A low-cost fabrication method is proposed for preparing close-packed nanofluidic channels for protein pre-concentration. The wrinkle pattern can be prepared by stretching a sheet of poly(dimethyl siloxane) (PDMS) and treating with oxygen plasma to produce stiff skin. The study applied strain to a PDMS sheet and then applied plasma treatment to the sheet. A strain directly applied on the PDMS layer with microfluidic channels during the study to produce inhomogeneous nanofluidic channels, the channels has three sides made of PDMS and one side made from glass. It was observed during the study that the WNCs can be integrated with microfluidic channels that further produce a functional and uniform nanochannel array. The study also found that the WNCs can produce uniform array of high density with controlled dimensions in a specified region.

UR - http://www.scopus.com/inward/record.url?scp=54949154899&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=54949154899&partnerID=8YFLogxK

U2 - 10.1002/adma.200701715

DO - 10.1002/adma.200701715

M3 - Article

VL - 20

SP - 3011

EP - 3016

JO - Advanced Materials

JF - Advanced Materials

SN - 0935-9648

IS - 16

ER -