Non-polydimethylsiloxane devices for oxygen-free flow lithography

Ki Wan Bong, Jingjing Xu, Jong Ho Kim, Stephen C. Chapin, Michael S. Strano, Karen K. Gleason, Patrick S. Doyle

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

Flow lithography has become a powerful particle synthesis technique. Currently, flow lithography relies on the use of polydimethylsiloxane microchannels, because the process requires local inhibition of polymerization, near channel interfaces, via oxygen permeation. The dependence on polydimethylsiloxane devices greatly limits the range of precursor materials that can be processed in flow lithography. Here we present oxygen-free flow lithography via inert fluid-lubrication layers for the synthesis of new classes of complex microparticles. We use an initiated chemical vapour deposition nano-adhesive bonding technique to create non-polydimethylsiloxane-based devices. We successfully synthesize microparticles with a sub-second residence time and demonstrate on-the-fly alteration of particle height. This technique greatly expands the synthesis capabilities of flow lithography, enabling particle synthesis, using water-insoluble monomers, organic solvents, and hydrophobic functional entities such as quantum dots and single-walled carbon nanotubes. As one demonstrative application, we created near-infrared barcoded particles for real-time, label-free detection of target analytes.

Original languageEnglish
Article number805
JournalNature Communications
Volume3
DOIs
Publication statusPublished - 2012 May 7
Externally publishedYes

Fingerprint

free flow
Lithography
lithography
Oxygen
Lubrication
Quantum Dots
Equipment and Supplies
Carbon Nanotubes
oxygen
Polymerization
Adhesives
microparticles
synthesis
Water
adhesive bonding
Single-walled carbon nanotubes (SWCN)
lubrication
microchannels
Microchannels
Permeation

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Chemistry(all)
  • Physics and Astronomy(all)

Cite this

Bong, K. W., Xu, J., Kim, J. H., Chapin, S. C., Strano, M. S., Gleason, K. K., & Doyle, P. S. (2012). Non-polydimethylsiloxane devices for oxygen-free flow lithography. Nature Communications, 3, [805]. https://doi.org/10.1038/ncomms1800

Non-polydimethylsiloxane devices for oxygen-free flow lithography. / Bong, Ki Wan; Xu, Jingjing; Kim, Jong Ho; Chapin, Stephen C.; Strano, Michael S.; Gleason, Karen K.; Doyle, Patrick S.

In: Nature Communications, Vol. 3, 805, 07.05.2012.

Research output: Contribution to journalArticle

Bong, KW, Xu, J, Kim, JH, Chapin, SC, Strano, MS, Gleason, KK & Doyle, PS 2012, 'Non-polydimethylsiloxane devices for oxygen-free flow lithography', Nature Communications, vol. 3, 805. https://doi.org/10.1038/ncomms1800
Bong, Ki Wan ; Xu, Jingjing ; Kim, Jong Ho ; Chapin, Stephen C. ; Strano, Michael S. ; Gleason, Karen K. ; Doyle, Patrick S. / Non-polydimethylsiloxane devices for oxygen-free flow lithography. In: Nature Communications. 2012 ; Vol. 3.
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