Nonblinking and nonbleaching upconverting nanoparticles as an optical imaging nanoprobe and T1 magnetic resonance imaging contrast agent

Yong Il Park; Jeong Hyun Kim; Kang Taek Lee; Ki Seok Jeon; Hyon Bin Na; Jung Ho Yu; Hyung Min Kim; Nohyun Lee; Seung Hong Choi; Sung Il Baik; Hyoungsu Kim; Seung Pyo Park; Beom Jin Park; Young Woon Kim; Sung Ho Lee; Soo Young Yoon; In Chan Song; Woo Kyung Moon; Yung Doug Suh; Taeghwan Hyeon

doi:10.1002/adma.200901356

Nonblinking and nonbleaching upconverting nanoparticles as an optical imaging nanoprobe and T1 magnetic resonance imaging contrast agent

Yong Il Park, Jeong Hyun Kim, Kang Taek Lee, Ki Seok Jeon, Hyon Bin Na, Jung Ho Yu, Hyung Min Kim, Nohyun Lee, Seung Hong Choi, Sung Il Baik, Hyoungsu Kim, Seung Pyo Park, Beom Jin Park, Young Woon Kim, Sung Ho Lee, Soo Young Yoon, In Chan Song, Woo Kyung Moon, Yung Doug Suh, Taeghwan Hyeon

Department of Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

507 Citations (Scopus)

Abstract

(Figure Presented) Core/shell upconverting nanoparticles (UCNPs) of NaGdF₄:Er³⁺,Yb³⁺/NaGdF₄ (see figure) are shown to serve as a multimodal imaging probe that works for both background-free optical imaging and magnetic resonance imaging (MRI). The nonblinking and nonbleaching properties of UCNPs can contribute to minimization of possible artifacts in long-term imaging experiments. Owing to Gd³⁺ ions in the host matrix, contrast is enhanced in T₁-weighted MRI.

Original language	English
Pages (from-to)	4467-4471
Number of pages	5
Journal	Advanced Materials
Volume	21
Issue number	44
DOIs	https://doi.org/10.1002/adma.200901356
Publication status	Published - 2009 Nov 26

ASJC Scopus subject areas

Materials Science(all)
Mechanics of Materials
Mechanical Engineering

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Park, Y. I., Kim, J. H., Lee, K. T., Jeon, K. S., Na, H. B., Yu, J. H., Kim, H. M., Lee, N., Choi, S. H., Baik, S. I., Kim, H., Park, S. P., Park, B. J., Kim, Y. W., Lee, S. H., Yoon, S. Y., Song, I. C., Moon, W. K., Suh, Y. D., & Hyeon, T. (2009). Nonblinking and nonbleaching upconverting nanoparticles as an optical imaging nanoprobe and T1 magnetic resonance imaging contrast agent. Advanced Materials, 21(44), 4467-4471. https://doi.org/10.1002/adma.200901356

Nonblinking and nonbleaching upconverting nanoparticles as an optical imaging nanoprobe and T1 magnetic resonance imaging contrast agent. / Park, Yong Il; Kim, Jeong Hyun; Lee, Kang Taek; Jeon, Ki Seok; Na, Hyon Bin; Yu, Jung Ho; Kim, Hyung Min; Lee, Nohyun; Choi, Seung Hong; Baik, Sung Il; Kim, Hyoungsu; Park, Seung Pyo; Park, Beom Jin; Kim, Young Woon; Lee, Sung Ho; Yoon, Soo Young; Song, In Chan; Moon, Woo Kyung; Suh, Yung Doug; Hyeon, Taeghwan.

In: Advanced Materials, Vol. 21, No. 44, 26.11.2009, p. 4467-4471.

Research output: Contribution to journal › Article › peer-review

Park, YI, Kim, JH, Lee, KT, Jeon, KS, Na, HB, Yu, JH, Kim, HM, Lee, N, Choi, SH, Baik, SI, Kim, H, Park, SP, Park, BJ, Kim, YW, Lee, SH, Yoon, SY, Song, IC, Moon, WK, Suh, YD & Hyeon, T 2009, 'Nonblinking and nonbleaching upconverting nanoparticles as an optical imaging nanoprobe and T1 magnetic resonance imaging contrast agent', Advanced Materials, vol. 21, no. 44, pp. 4467-4471. https://doi.org/10.1002/adma.200901356

Park, Yong Il ; Kim, Jeong Hyun ; Lee, Kang Taek ; Jeon, Ki Seok ; Na, Hyon Bin ; Yu, Jung Ho ; Kim, Hyung Min ; Lee, Nohyun ; Choi, Seung Hong ; Baik, Sung Il ; Kim, Hyoungsu ; Park, Seung Pyo ; Park, Beom Jin ; Kim, Young Woon ; Lee, Sung Ho ; Yoon, Soo Young ; Song, In Chan ; Moon, Woo Kyung ; Suh, Yung Doug ; Hyeon, Taeghwan. / Nonblinking and nonbleaching upconverting nanoparticles as an optical imaging nanoprobe and T1 magnetic resonance imaging contrast agent. In: Advanced Materials. 2009 ; Vol. 21, No. 44. pp. 4467-4471.

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abstract = "(Figure Presented) Core/shell upconverting nanoparticles (UCNPs) of NaGdF4:Er3+,Yb3+/NaGdF4 (see figure) are shown to serve as a multimodal imaging probe that works for both background-free optical imaging and magnetic resonance imaging (MRI). The nonblinking and nonbleaching properties of UCNPs can contribute to minimization of possible artifacts in long-term imaging experiments. Owing to Gd3+ ions in the host matrix, contrast is enhanced in T1-weighted MRI.",

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AU - Yu, Jung Ho

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AU - Baik, Sung Il

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AU - Yoon, Soo Young

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AU - Hyeon, Taeghwan

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AB - (Figure Presented) Core/shell upconverting nanoparticles (UCNPs) of NaGdF4:Er3+,Yb3+/NaGdF4 (see figure) are shown to serve as a multimodal imaging probe that works for both background-free optical imaging and magnetic resonance imaging (MRI). The nonblinking and nonbleaching properties of UCNPs can contribute to minimization of possible artifacts in long-term imaging experiments. Owing to Gd3+ ions in the host matrix, contrast is enhanced in T1-weighted MRI.

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Nonblinking and nonbleaching upconverting nanoparticles as an optical imaging nanoprobe and T1 magnetic resonance imaging contrast agent

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