Nonblinking and nonbleaching upconverting nanoparticles as an optical imaging nanoprobe and T1 magnetic resonance imaging contrast agent

Yong Il Park, Jeong Hyun Kim, Kang Taek Lee, Ki Seok Jeon, Hyon Bin Na, Jung Ho Yu, Hyung Min Kim, Nohyun Lee, Seung Hong Choi, Sung Il Baik, Hyoungsu Kim, Seung Pyo Park, Beom Jin Park, Young Woon Kim, Sung Ho Lee, Soo Young Yoon, In Chan Song, Woo Kyung Moon, Yung Doug Suh, Taeghwan Hyeon

Research output: Contribution to journalArticlepeer-review

496 Citations (Scopus)

Abstract

(Figure Presented) Core/shell upconverting nanoparticles (UCNPs) of NaGdF4:Er3+,Yb3+/NaGdF4 (see figure) are shown to serve as a multimodal imaging probe that works for both background-free optical imaging and magnetic resonance imaging (MRI). The nonblinking and nonbleaching properties of UCNPs can contribute to minimization of possible artifacts in long-term imaging experiments. Owing to Gd3+ ions in the host matrix, contrast is enhanced in T1-weighted MRI.

Original languageEnglish
Pages (from-to)4467-4471
Number of pages5
JournalAdvanced Materials
Volume21
Issue number44
DOIs
Publication statusPublished - 2009 Nov 26

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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