Noncontact measurement of nerve displacement during action potential with a dual-beam low-coherence interferometer

Christopher Fang-Yen, Mark C. Chu, H. Sebastian Seung, Ramachandra R. Dasari, Michael S. Feld

Research output: Contribution to journalArticle

80 Citations (Scopus)

Abstract

We have used a novel phase-referenced heterodyne dual-beam low-coherence interferometer to perform what we believe are the first noncontact measurements of surface motion in a nerve bundle during the action potential. Nerve displacements of ∼5-nm amplitude and ∼10-ms duration are measured without signal averaging. This interferometer may find general application in measurement of small motion in cells and other weakly scattering samples.

Original languageEnglish
Pages (from-to)2028-2030
Number of pages3
JournalOptics Letters
Volume29
Issue number17
DOIs
Publication statusPublished - 2004 Sep 1

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

Fingerprint Dive into the research topics of 'Noncontact measurement of nerve displacement during action potential with a dual-beam low-coherence interferometer'. Together they form a unique fingerprint.

  • Cite this