"Nondefect" of arterial enhancing rim on hepatobiliary phase in 3.0-T gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced liver magnetic resonance imaging: Distinguishing hepatic abscess from metastasis

Seung Hee Choi, Chang Hee Lee, Baek Hui Kim, Jongmee Lee, Jae Woong Choi, Yang Shin Park, Kyeong Ah Kim, Cheol Min Park

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6 Citations (Scopus)


OBJECTIVE: The objective of this study was to retrospectively determine the findings of Gd-EOB-DTPA (gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid)-enhanced magnetic resonance imaging (MRI) to distinguish abscess from metastasis of the liver. METHODS: Among patients who underwent Gd-EOB-DTPA MRI from March 2008 to December 2011, 32 patients with abscess or metastasis were included, and all lesions showed arterial rim enhancement. Twenty-one abscesses and 19 metastases were included. Two radiologists assessed how the arterial enhancing rim showed in hepatobiliary phase (HBP) and classified the signal intensity of the rim into defect zone, gray zone, and uptake zone. The frequency of showing nondefect, which means gray or uptake zone between both lesions, was compared using Pearson χ test. RESULTS: The rim of arterial enhancement in 3 abscesses (14.3%) and 15 metastases (78.9%) showed defect zone in HBP. Six abscesses (28.6%)and no metastases showed gray zone, and 12 abscesses (57.1%) and 4 metastases (21.1%) showed uptake zone. The frequency of nondefect in the rim of arterial enhancement on HBP was significantly higher in abscesses (85.7% of abscesses, 21.1% of metastases, P < 0.001). CONCLUSIONS: A reliable finding that distinguished abscess from metastasis was nondefect of arterial enhancing rim on HBP in Gd-EOB-DTPA MRI. This is a meaningful feature for differentiating abscess from metastasis, especially when evaluating patients with primary malignancy.

Original languageEnglish
Pages (from-to)849-855
Number of pages7
JournalJournal of Computer Assisted Tomography
Issue number6
Publication statusPublished - 2013 Nov 1



  • MRI
  • abscess
  • gadoxetic acid
  • liver
  • metastasis

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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