Abstract
Objectives: Based on the evidence that the dorsolateral prefrontal cortex (DLPFC) is the main region affected by the aging process, and that tDCS modulates cortical excitability, the aim of the study is to prove the feasibility of tDCS for pain perception and executive function of community-dwelling elderly individuals. Methods: We performed a double-blind, single-arm trial, including a sham period. 5 consecutive anodal tDCS was applied over DLPFC of twenty-four elderly for 20 min during each intervention periods (in order of Sham-1 mA–2 mA). First, we classified chronic non-inflammatory pain sites into three domain (Neck and upper extremity, low back, lower extremity). Then, we used visual analogue scale, pain self-efficacy scale, Tampa scale for kinesiophobia, and Global perceived Effect scale to observe the change in pain perception, as well as Trailing Making Test and Timed Up and Go (dual) to observe the change in executive function. The changes in maximal grip strength and 12-item Short Form survey were measured secondarily. Results: In the results, we observed significant improvement in pain perception and quality of life, while executive function and grip strength did not change significantly. Conclusion: Our findings demonstrated the feasibility of tDCS for aging-related pain perception and suggest that further randomized controlled trials with longer duration are necessary to examine the effects on executive function.
| Original language | English |
|---|---|
| Pages (from-to) | 252-257 |
| Number of pages | 6 |
| Journal | Archives of Gerontology and Geriatrics |
| Volume | 81 |
| DOIs | |
| Publication status | Published - 2019 Mar 1 |
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Keywords
- Aging
- Cognitive function
- Pain perception
- Prefrontal cortex
- Transcranial direct current stimulation
ASJC Scopus subject areas
- Health(social science)
- Ageing
- Gerontology
- Geriatrics and Gerontology
Cite this
Noninvasive brain stimulation over dorsolateral prefrontal cortex for pain perception and executive function in aging. / Lee, Jae Hyuk; Jin, Yan; Oh, Se Jun; Lim, Tae Hyun; Yoon, Bum-Chul.
In: Archives of Gerontology and Geriatrics, Vol. 81, 01.03.2019, p. 252-257.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Noninvasive brain stimulation over dorsolateral prefrontal cortex for pain perception and executive function in aging
AU - Lee, Jae Hyuk
AU - Jin, Yan
AU - Oh, Se Jun
AU - Lim, Tae Hyun
AU - Yoon, Bum-Chul
PY - 2019/3/1
Y1 - 2019/3/1
N2 - Objectives: Based on the evidence that the dorsolateral prefrontal cortex (DLPFC) is the main region affected by the aging process, and that tDCS modulates cortical excitability, the aim of the study is to prove the feasibility of tDCS for pain perception and executive function of community-dwelling elderly individuals. Methods: We performed a double-blind, single-arm trial, including a sham period. 5 consecutive anodal tDCS was applied over DLPFC of twenty-four elderly for 20 min during each intervention periods (in order of Sham-1 mA–2 mA). First, we classified chronic non-inflammatory pain sites into three domain (Neck and upper extremity, low back, lower extremity). Then, we used visual analogue scale, pain self-efficacy scale, Tampa scale for kinesiophobia, and Global perceived Effect scale to observe the change in pain perception, as well as Trailing Making Test and Timed Up and Go (dual) to observe the change in executive function. The changes in maximal grip strength and 12-item Short Form survey were measured secondarily. Results: In the results, we observed significant improvement in pain perception and quality of life, while executive function and grip strength did not change significantly. Conclusion: Our findings demonstrated the feasibility of tDCS for aging-related pain perception and suggest that further randomized controlled trials with longer duration are necessary to examine the effects on executive function.
AB - Objectives: Based on the evidence that the dorsolateral prefrontal cortex (DLPFC) is the main region affected by the aging process, and that tDCS modulates cortical excitability, the aim of the study is to prove the feasibility of tDCS for pain perception and executive function of community-dwelling elderly individuals. Methods: We performed a double-blind, single-arm trial, including a sham period. 5 consecutive anodal tDCS was applied over DLPFC of twenty-four elderly for 20 min during each intervention periods (in order of Sham-1 mA–2 mA). First, we classified chronic non-inflammatory pain sites into three domain (Neck and upper extremity, low back, lower extremity). Then, we used visual analogue scale, pain self-efficacy scale, Tampa scale for kinesiophobia, and Global perceived Effect scale to observe the change in pain perception, as well as Trailing Making Test and Timed Up and Go (dual) to observe the change in executive function. The changes in maximal grip strength and 12-item Short Form survey were measured secondarily. Results: In the results, we observed significant improvement in pain perception and quality of life, while executive function and grip strength did not change significantly. Conclusion: Our findings demonstrated the feasibility of tDCS for aging-related pain perception and suggest that further randomized controlled trials with longer duration are necessary to examine the effects on executive function.
KW - Aging
KW - Cognitive function
KW - Pain perception
KW - Prefrontal cortex
KW - Transcranial direct current stimulation
UR - http://www.scopus.com/inward/record.url?scp=85056573752&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85056573752&partnerID=8YFLogxK
U2 - 10.1016/j.archger.2018.10.002
DO - 10.1016/j.archger.2018.10.002
M3 - Article
C2 - 30459016
AN - SCOPUS:85056573752
VL - 81
SP - 252
EP - 257
JO - Archives of Gerontology and Geriatrics
JF - Archives of Gerontology and Geriatrics
SN - 0167-4943
ER -