Nonsolvent induced phase separation (NIPS)-based 3D plotting for 3-dimensionally macrochanneled poly(ε-caprolactone) scaffolds with highly porous frameworks

Kwan Ha Shin, In Hwan Jo, Sung Eun Kim, Young Hag Koh, Hyoun Ee Kim

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

This study demonstrates the utility of nonsolvent induced phase separation (NIPS)-based 3D plotting as a novel SFF technique for the production of 3-dimensionally macrochanneled poly(ε-caprolactone) (PCL) scaffolds with highly porous PCL frameworks. In particular, a PCL/tetrahydrofuran (THF) solution was deposited in an EtOH bath to rapidly solidify PCL filaments with a highly porous structure through exchange of THF solvent and EtOH nonsolvent. All the scaffolds produced with various PCL concentrations (14 wt%, 18 wt%, and 22 wt%) showed well-constructed 3-D macrochannels with highly porous PCL frameworks. However, the mechanical properties of the scaffolds, measured by compressive and tensile strength tests, increased with an increase in PCL concentration owing to a decrease in the overall porosity.

Original languageEnglish
Pages (from-to)348-351
Number of pages4
JournalMaterials Letters
Volume122
DOIs
Publication statusPublished - 2014 May 1

Keywords

  • Biomaterials
  • Composite materials
  • Polymers
  • Porous materials

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

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