Nontuberculous mycobacterial lung disease caused by mycobacterium simiae: The first reported case in South Korea

Suk Hyeon Jeong, Su Young Kim, Hyun Lee, Jun Soo Ham, Keum Bit Hwang, Subin Hwang, Sun Hye Shin, Myung Jin Chung, Seung Heon Lee, Sung Jae Shin, Won Jung Koh

    Research output: Contribution to journalArticlepeer-review

    3 Citations (Scopus)

    Abstract

    This is a report of the first South Korean case of a lung disease caused by Mycobacterium simiae. The patient was a previously healthy 52-year-old female. All serial isolates were identified as M. simiae by multi-locus sequencing analysis, based on hsp65, rpoB, 16S-23S rRNA internal transcribed spacer, and 16S rRNA fragments. A chest radiography revealed deterioration, and the follow-up sputum cultures were persistently positive, despite combination antibiotic treatment, including azithromycin, ethambutol, and rifampin. To the best of our knowledge, this is the first confirmed case of a lung disease caused by M. simiae in South Korea.

    Original languageEnglish
    Pages (from-to)432-435
    Number of pages4
    JournalTuberculosis and Respiratory Diseases
    Volume78
    Issue number4
    DOIs
    Publication statusPublished - 2015 Oct 1

    Keywords

    • Bronchiectasis
    • Mycobacterium
    • Nontuberculous mycobacteria

    ASJC Scopus subject areas

    • Pulmonary and Respiratory Medicine
    • Infectious Diseases

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