Normal 2-dimensional strain values of the left ventricle: A substudy of the normal echocardiographic measurements in Korean population study

Jae Hyeong Park, Ju Hee Lee, Sang Yeub Lee, Jin Oh Choi, Mi Seung Shin, Mi Jeong Kim, Hae Ok Jung, Jeong Rang Park, Il Suk Sohn, Hyungseop Kim, Seong Mi Park, Nam Jin Yo, Jung Hyun Cho, Hyung Kwan Kim, Goo Yeong Cho, Mi Rae Lee, Jin Sun Park, Chi Young Shim, Dae Hee Kim, Dae Hee ShinGil Ja Shin, Sung Hee Shin, Kye Hun Kim, Woo Shik Kim, Seung Woo Park

    Research output: Contribution to journalArticlepeer-review

    18 Citations (Scopus)


    Background: It is important to understand the distribution of 2-dimensional strain values in normal population. We performed a multicenter trial to measure normal echocardiographic values in the Korean population. Methods: This was a substudy of the Normal echOcardiogRaphic Measurements in KoreAn popuLation (NORMAL) study. Echocardiographic specialists measured frequently used echocardiographic indices in healthy people according to a standardized method at 23 different university hospitals. The strain values were analyzed from digitally stored images. Results: Of a total of 1003 healthy participants in NORMAL study, 2-dimensional strain values were measured in 501 subjects (265 females, mean age 47 ± 15 years old) with echocardiographic images only by GE echocardiographic machines. Interventricular septal thickness, left ventricular (LV) posterior wall thickness, systolic and diastolic LV dimensions, and LV ejection fraction were 7.5 ± 1.0 mm, 7.4 ± 1.0 mm, 29.9 ± 2.8 mm, 48.9 ± 3.6 mm, and 62 ± 4%, respectively. LV longitudinal systolic strain (LS) values of apical 4-chamber (A4C) view, apical 3-chamber (A3C) view, apical 2-chamber (A2C) view, and LV global LS (LVGLS) were -20.1 ± 2.3, -19.9 ± 2.7, -21.2 ± 2.6, and -20.4 ± 2.2%, respectively. LV longitudinal systolic strain rate (LVLSR) values of the A4C view, A3C view, A2C view, and LV global LSR (LVGLSR) were -1.18 ± 0.18, -1.20 ± 0.21, -1.25 ± 0.21, and -1.21 ± 0.21-s, respectively. Females had lower LVGLS (-21.2 ± 2.2% vs. -19.5 ± 1.9%, p < 0.001) and LVGLSR (-1.25 ± 0.18-s vs. -1.17 ± 0.15-s, p < 0.001) values than males. Conclusion: We measured LV longitudinal strain and strain rate values in the normal Korean population. Since considerable gender differences were observed, normal echocardiographic cutoff values should be differentially applied based on sex.

    Original languageEnglish
    Pages (from-to)285-293
    Number of pages9
    JournalJournal of Cardiovascular Ultrasound
    Issue number4
    Publication statusPublished - 2016 Dec


    • Echocardiography
    • Normal population
    • Reference value
    • Strain

    ASJC Scopus subject areas

    • Radiology Nuclear Medicine and imaging
    • Cardiology and Cardiovascular Medicine


    Dive into the research topics of 'Normal 2-dimensional strain values of the left ventricle: A substudy of the normal echocardiographic measurements in Korean population study'. Together they form a unique fingerprint.

    Cite this