Novel calcium-binding GTPase (AtCBG) involved in ABA-mediated salt stress signaling in Arabidopsis

Kandakumar Jayasekaran, Kyung Nam Kim, Munusamy Vivekanandan, Jeong Sheop Shin, Sung Han Ok

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

We have identified a novel Ca2+-signal sensing GTPase (643 amino acid residues with an estimated molecular mass of 79 kDa) from the Arabidopsis genome database. This protein contains a RHO-like GTPase domain at the N-terminus (15-184 amino acids) and two calcium-binding EF-hand motifs (199-227 and 319-347 amino acids, respectively). It has the capability to bind calcium and hydrolyze GTP; in addition, its GTPase activity is regulated by changes in Ca2+ concentration. The expression of this gene was induced by ABA and salt stresses, and specific knock-out mutants were highly sensitive to ABA and salt treatments. These findings suggest that this protein is a novel ABA- and salt stress-related Ca2+ signal transducer.

Original languageEnglish
Pages (from-to)1255-1262
Number of pages8
JournalPlant Cell Reports
Volume25
Issue number11
DOIs
Publication statusPublished - 2006 Nov

Keywords

  • Abiotic stress
  • Ca
  • GTP-binding
  • Regulation of gene expression
  • Signal transduction

ASJC Scopus subject areas

  • Agronomy and Crop Science
  • Plant Science

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