Novel fabrication of a polymer scaffold with a dense bioactive ceramic coating layer

In Kook Jun, Young Hag Koh, Su Hee Lee, Hyoun Ee Kim

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

A novel method of coating a polymeric scaffold with a dense ceramic layer was developed. This method exploits the fact that only one of the two interlaced 3-D channels formed in a ceramic dual-scaffold can be infiltrated with a polymer. Firstly, a 3-D graphite network prepared by the rapid prototyping (RP) method was dip-coated with hydroxyapatite (HA) slurry, followed by heat-treatment at 1250°C for 3 h in air. This created an additional 3-D channel through the removal of the graphite network, while preserving the pre-existing 3-D channel. Thereafter, only one channel was infiltrated with a molten poly(ε-caprolactone) (PCL) polymer at 140°C for 12 h, producing a PCL scaffold with a dense, uniform HA coating layer. The sample showed high compressive strength with ductile behavior, due to the nature of the PCL polymer, and an excellent cellular response afforded by the bioactive HA coating layer. The results indicate that this novel technique provides a highly versatile method of coating various polymeric scaffolds with bioactive layers in order to endow them with advanced functionalities.

Original languageEnglish
Pages (from-to)1537-1542
Number of pages6
JournalJournal of Materials Science: Materials in Medicine
Volume18
Issue number8
DOIs
Publication statusPublished - 2007 Aug
Externally publishedYes

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Biomedical Engineering

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