Novel fabrication of a polymer scaffold with a dense bioactive ceramic coating layer

In Kook Jun, Young-Hag Koh, Su H. Lee, Hyoun E. Kim

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

A novel method of coating a polymeric scaffold with a dense ceramic layer was developed. This method exploits the fact that only one of the two interlaced 3-D channels formed in a ceramic dual-scaffold can be infiltrated with a polymer. Firstly, a 3-D graphite network prepared by the rapid prototyping (RP) method was dip-coated with hydroxyapatite (HA) slurry, followed by heat-treatment at 1250°C for 3 h in air. This created an additional 3-D channel through the removal of the graphite network, while preserving the pre-existing 3-D channel. Thereafter, only one channel was infiltrated with a molten poly(ε-caprolactone) (PCL) polymer at 140°C for 12 h, producing a PCL scaffold with a dense, uniform HA coating layer. The sample showed high compressive strength with ductile behavior, due to the nature of the PCL polymer, and an excellent cellular response afforded by the bioactive HA coating layer. The results indicate that this novel technique provides a highly versatile method of coating various polymeric scaffolds with bioactive layers in order to endow them with advanced functionalities.

Original languageEnglish
Pages (from-to)1537-1542
Number of pages6
JournalJournal of Materials Science: Materials in Medicine
Volume18
Issue number8
DOIs
Publication statusPublished - 2007 Aug 1
Externally publishedYes

Fingerprint

ceramic coatings
Ceramic coatings
Ceramics
activity (biology)
Scaffolds
Polymers
Durapatite
Hydroxyapatite
Fabrication
Coatings
fabrication
Graphite
polymers
coating
graphite
ceramics
Compressive Strength
coatings
rapid prototyping
compressive strength

ASJC Scopus subject areas

  • Biophysics
  • Chemical Engineering(all)
  • Bioengineering

Cite this

Novel fabrication of a polymer scaffold with a dense bioactive ceramic coating layer. / Jun, In Kook; Koh, Young-Hag; Lee, Su H.; Kim, Hyoun E.

In: Journal of Materials Science: Materials in Medicine, Vol. 18, No. 8, 01.08.2007, p. 1537-1542.

Research output: Contribution to journalArticle

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