Nucleosides with modified sugar ring: Synthesis and biological activities

Sarbjit Singh, Deepak Bhattarai, Gajulapati Veeraswamy, Yongseok Choi, Kyeong Lee

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

In the recent few years, the emergence of nucleosides containing modified sugar ring or modified base moiety has gained much attention due to their enhanced biological activities as compared to parent nucleosides containing 5-carbon ribose or deoxyribose sugar ring. In this review, we highlight the recent advances in synthesis and biological activities of nucleosides containing modified sugar rings reported between years 2010 to 2015.

Original languageEnglish
Pages (from-to)856-897
Number of pages42
JournalCurrent Organic Chemistry
Volume20
Issue number8
Publication statusPublished - 2016 Apr 1

Keywords

  • Biologically active nucleosides
  • Fluorinated nucleosides
  • Functionalized nucleosides
  • Modified nucleosides
  • Selenonucleosides
  • Thionucleosides

ASJC Scopus subject areas

  • Organic Chemistry

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  • Cite this

    Singh, S., Bhattarai, D., Veeraswamy, G., Choi, Y., & Lee, K. (2016). Nucleosides with modified sugar ring: Synthesis and biological activities. Current Organic Chemistry, 20(8), 856-897.