Occurrences of major polybrominated diphenyl ethers (PBDEs) in maternal and fetal cord blood sera in Korea

Gyuyeon Choi, Sungjoo Kim, Sunmi Kim, Sungkyoon Kim, Youngeun Choi, Hai Joong Kim, Jeong Jae Lee, Su Young Kim, Sunggyu Lee, Hyo Bang Moon, Sooran Choi, Kyungho Choi, Jeongim Park

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Polybrominated diphenyl ethers (PBDEs) are of growing public health concern because of their potential toxicities which range from endocrine disruption to neurodevelopment. However, information on their exposure among sensitive human populations is limited. The objectives of this study were to determine the levels of major PBDEs in blood sera of pregnant women and their matching newborn infants. For this purpose, a total of 198 maternal blood samples and 118 matching umbilical cord blood samples were collected from four regions of South Korea in 2011, and were determined for 19 PBDE congeners. Various demographic, dietary, and behavioral characteristics were asked in a questionnaire survey. Average concentration of total PBDEs in maternal blood serum was 3.34 ± 8.42. ng/g lipid weight (lw) at delivery and 3.14 ± 7.46. ng/g lw at 6. months of pregnancy, respectively. In cord blood serum, an average of 9.37 ± 12.60. ng/g lw was detected. Among the measured PBDE congeners, BDE-47, BDE-99 and BDE-153 were most dominant in both maternal and cord blood sera. Relatively higher levels of BDE-99 were detected in cord blood serum. Strong positive correlations were detected between maternal and cord blood serum samples, indicating the importance of maternal transfer. Health consequences of transplacental exposure to PBDEs among fetuses and newborn infants warrant further investigation.

Original languageEnglish
Pages (from-to)219-226
Number of pages8
JournalScience of the Total Environment
Volume491-492
DOIs
Publication statusPublished - 2014 Sep 1

Fingerprint

Halogenated Diphenyl Ethers
PBDE
serum
Ethers
Blood
blood
Lipids
lipid
questionnaire survey
Public health
pregnancy
Toxicity
public health
Health
toxicity

Keywords

  • BDE-153
  • BDE-47
  • BDE-99
  • Infant
  • Pregnant women
  • Transplacental

ASJC Scopus subject areas

  • Environmental Engineering
  • Environmental Chemistry
  • Waste Management and Disposal
  • Pollution

Cite this

Occurrences of major polybrominated diphenyl ethers (PBDEs) in maternal and fetal cord blood sera in Korea. / Choi, Gyuyeon; Kim, Sungjoo; Kim, Sunmi; Kim, Sungkyoon; Choi, Youngeun; Kim, Hai Joong; Lee, Jeong Jae; Kim, Su Young; Lee, Sunggyu; Moon, Hyo Bang; Choi, Sooran; Choi, Kyungho; Park, Jeongim.

In: Science of the Total Environment, Vol. 491-492, 01.09.2014, p. 219-226.

Research output: Contribution to journalArticle

Choi, G, Kim, S, Kim, S, Kim, S, Choi, Y, Kim, HJ, Lee, JJ, Kim, SY, Lee, S, Moon, HB, Choi, S, Choi, K & Park, J 2014, 'Occurrences of major polybrominated diphenyl ethers (PBDEs) in maternal and fetal cord blood sera in Korea', Science of the Total Environment, vol. 491-492, pp. 219-226. https://doi.org/10.1016/j.scitotenv.2014.02.071
Choi, Gyuyeon ; Kim, Sungjoo ; Kim, Sunmi ; Kim, Sungkyoon ; Choi, Youngeun ; Kim, Hai Joong ; Lee, Jeong Jae ; Kim, Su Young ; Lee, Sunggyu ; Moon, Hyo Bang ; Choi, Sooran ; Choi, Kyungho ; Park, Jeongim. / Occurrences of major polybrominated diphenyl ethers (PBDEs) in maternal and fetal cord blood sera in Korea. In: Science of the Total Environment. 2014 ; Vol. 491-492. pp. 219-226.
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