TY - JOUR
T1 - Ocular perfusion pressure and choroidal thickness in central serous chorioretinopathy and pigment epitheliopathy
AU - Yun, Cheolmin
AU - Han, Ji Yun
AU - Cho, Sungwon
AU - Hwang, Soon Young
AU - Kim, Seong Woo
AU - Oh, Jaeryung
N1 - Funding Information:
Supported by the Ministry of Trade, Industry, and Energy (MO-TIE, South Korea) under the Industrial Technology Innovation (10063364).
Funding Information:
Supported by the Ministry of Trade, Industry, and Energy (MOTIE, South Korea) under the Industrial Technology Innovation (10063364).
Publisher Copyright:
© 2020 EDP Sciences. All rights reserved.
PY - 2019
Y1 - 2019
N2 - Purpose:To investigate ocular perfusion pressure (OPP) in patients with central serous chorioretinopathy (CSC) and pigment epitheliopathy (PE).Methods:In this retrospective study, we included patients with acute idiopathic unilateral CSC and age- and sex-matched normal controls. The patients with CSC were classified into two groups according to the PE presence on their fellow eyes. We compared OPP among CSC patients with or without PE and normal controls.Results:Among a total of 47 patients with CSC, 21 were classified into the PE group and 26 into the non-PE group. The mean OPP (±SD) of CSC and fellow eyes in the PE group (50.02 ± 4.98 and 50.83 ± 4.12 mmHg, respectively) was greater than that in the non-PE group (43.69 ± 6.88 and 44.0 ± 6.57 mmHg, respectively) and normal controls (45.64 ± 8.73 mmHg) (all, P < 0.05). The mean macular choroidal thickness of CSC and fellow eyes in the PE group (344.4 ± 31.8 and 310.1 ± 37.0 m, respectively) was thicker than that in the non-PE group (318.5 ± 43.8 and 282.8 ± 36.1 m, respectively) (all, P < 0.05). Greater macular choroidal thickness and higher OPP were associated with PE (P = 0.002 and P = 0.003).Conclusion:Forty-five percent of the patients with acute unilateral CSC had PE in their fellow eyes. Increased OPP may influence the development of bilateral CSC characteristics.
AB - Purpose:To investigate ocular perfusion pressure (OPP) in patients with central serous chorioretinopathy (CSC) and pigment epitheliopathy (PE).Methods:In this retrospective study, we included patients with acute idiopathic unilateral CSC and age- and sex-matched normal controls. The patients with CSC were classified into two groups according to the PE presence on their fellow eyes. We compared OPP among CSC patients with or without PE and normal controls.Results:Among a total of 47 patients with CSC, 21 were classified into the PE group and 26 into the non-PE group. The mean OPP (±SD) of CSC and fellow eyes in the PE group (50.02 ± 4.98 and 50.83 ± 4.12 mmHg, respectively) was greater than that in the non-PE group (43.69 ± 6.88 and 44.0 ± 6.57 mmHg, respectively) and normal controls (45.64 ± 8.73 mmHg) (all, P < 0.05). The mean macular choroidal thickness of CSC and fellow eyes in the PE group (344.4 ± 31.8 and 310.1 ± 37.0 m, respectively) was thicker than that in the non-PE group (318.5 ± 43.8 and 282.8 ± 36.1 m, respectively) (all, P < 0.05). Greater macular choroidal thickness and higher OPP were associated with PE (P = 0.002 and P = 0.003).Conclusion:Forty-five percent of the patients with acute unilateral CSC had PE in their fellow eyes. Increased OPP may influence the development of bilateral CSC characteristics.
KW - central serous chorioretinopathy
KW - choroidal thickness
KW - ocular perfusion pressure
KW - pachychoroidal spectrum disease
KW - pigment epitheliopathy
UR - http://www.scopus.com/inward/record.url?scp=85058887955&partnerID=8YFLogxK
U2 - 10.1097/IAE.0000000000001916
DO - 10.1097/IAE.0000000000001916
M3 - Article
C2 - 29095356
AN - SCOPUS:85058887955
SN - 0275-004X
VL - 39
SP - 143
EP - 149
JO - Retina
JF - Retina
IS - 1
ER -