Off-site evaluation of three-dimensional ultrasound for the diagnosis of thyroid nodules: comparison with two-dimensional ultrasound

Soo Chin Kim, Ji hoon Kim, Seung Hong Choi, Tae Jin Yun, Jae Yeon Wi, Sun Ah Kim, Hye Young Sun, Inseon Ryoo, Sun Won Park, Chul Ho Sohn

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Objectives: We compared the diagnostic performance of off-site evaluation between prospectively obtained 3D and 2D ultrasound for thyroid nodules. Methods: 3D and 2D ultrasonographies were preoperatively obtained from 85 consecutive patients (mean age, 51 years; age range, 28–83 years) who were referred for a total thyroidectomy. Three radiologists independently evaluated 3D and 2D images of 91 pathologically confirmed thyroid nodules (30 benign and 61 malignant nodules) for nodule characterization. Diagnostic performance, interobserver agreement and time for scanning were compared between 3D and 2D. Results: 3D had significantly higher sensitivities than 2D for predicting malignancy (78.7 % vs. 61.2 %, P < 0.01) and extrathyroidal extension (66.7 % vs. 46.4 %, P = 0.03) in malignancy. In terms of specificities, there were no statistically significant differences between 2D and 3D for predicting malignancy (78.4 % vs. 74.8 %, P = 1.00) and extrathyroidal extension (63.6 % vs. 57.6 %, P = 0.46). With respect to interobserver agreement, 3D showed moderate agreement (κ = 0.53) for predicting extrathyroidal extension in malignancy compared with 2D ultrasound, which showed fair agreement (κ = 0.37). 3D saved time (30 ± 56.52 s) for scanning compared with 2D. Conclusion: For off-site evaluation, 3D US is more useful for diagnosis of thyroid nodules than 2D US. Key Points: • 3D had higher sensitivity than 2D for predicting malignancy and extrathyroidal extension. • 3D showed better agreement for predicting extrathyroidal extension in malignancy than 2D. • 3D thyroid ultrasound saved time for scanning compared with 2D. • For off-site evaluation of thyroid nodules, 3D is more useful than 2D.

Original languageEnglish
Pages (from-to)3353-3360
Number of pages8
JournalEuropean Radiology
Volume26
Issue number10
DOIs
Publication statusPublished - 2016 Oct 1

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Thyroid Nodule
Neoplasms
Thyroidectomy
Ultrasonography
Thyroid Gland

Keywords

  • Diagnosis
  • Off-site evaluation
  • Three-dimensional ultrasound
  • Thyroid nodule
  • Two-dimensional ultrasound

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Off-site evaluation of three-dimensional ultrasound for the diagnosis of thyroid nodules : comparison with two-dimensional ultrasound. / Kim, Soo Chin; Kim, Ji hoon; Choi, Seung Hong; Yun, Tae Jin; Wi, Jae Yeon; Kim, Sun Ah; Sun, Hye Young; Ryoo, Inseon; Park, Sun Won; Sohn, Chul Ho.

In: European Radiology, Vol. 26, No. 10, 01.10.2016, p. 3353-3360.

Research output: Contribution to journalArticle

Kim, Soo Chin ; Kim, Ji hoon ; Choi, Seung Hong ; Yun, Tae Jin ; Wi, Jae Yeon ; Kim, Sun Ah ; Sun, Hye Young ; Ryoo, Inseon ; Park, Sun Won ; Sohn, Chul Ho. / Off-site evaluation of three-dimensional ultrasound for the diagnosis of thyroid nodules : comparison with two-dimensional ultrasound. In: European Radiology. 2016 ; Vol. 26, No. 10. pp. 3353-3360.
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abstract = "Objectives: We compared the diagnostic performance of off-site evaluation between prospectively obtained 3D and 2D ultrasound for thyroid nodules. Methods: 3D and 2D ultrasonographies were preoperatively obtained from 85 consecutive patients (mean age, 51 years; age range, 28–83 years) who were referred for a total thyroidectomy. Three radiologists independently evaluated 3D and 2D images of 91 pathologically confirmed thyroid nodules (30 benign and 61 malignant nodules) for nodule characterization. Diagnostic performance, interobserver agreement and time for scanning were compared between 3D and 2D. Results: 3D had significantly higher sensitivities than 2D for predicting malignancy (78.7 {\%} vs. 61.2 {\%}, P < 0.01) and extrathyroidal extension (66.7 {\%} vs. 46.4 {\%}, P = 0.03) in malignancy. In terms of specificities, there were no statistically significant differences between 2D and 3D for predicting malignancy (78.4 {\%} vs. 74.8 {\%}, P = 1.00) and extrathyroidal extension (63.6 {\%} vs. 57.6 {\%}, P = 0.46). With respect to interobserver agreement, 3D showed moderate agreement (κ = 0.53) for predicting extrathyroidal extension in malignancy compared with 2D ultrasound, which showed fair agreement (κ = 0.37). 3D saved time (30 ± 56.52 s) for scanning compared with 2D. Conclusion: For off-site evaluation, 3D US is more useful for diagnosis of thyroid nodules than 2D US. Key Points: • 3D had higher sensitivity than 2D for predicting malignancy and extrathyroidal extension. • 3D showed better agreement for predicting extrathyroidal extension in malignancy than 2D. • 3D thyroid ultrasound saved time for scanning compared with 2D. • For off-site evaluation of thyroid nodules, 3D is more useful than 2D.",
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AU - Yun, Tae Jin

AU - Wi, Jae Yeon

AU - Kim, Sun Ah

AU - Sun, Hye Young

AU - Ryoo, Inseon

AU - Park, Sun Won

AU - Sohn, Chul Ho

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N2 - Objectives: We compared the diagnostic performance of off-site evaluation between prospectively obtained 3D and 2D ultrasound for thyroid nodules. Methods: 3D and 2D ultrasonographies were preoperatively obtained from 85 consecutive patients (mean age, 51 years; age range, 28–83 years) who were referred for a total thyroidectomy. Three radiologists independently evaluated 3D and 2D images of 91 pathologically confirmed thyroid nodules (30 benign and 61 malignant nodules) for nodule characterization. Diagnostic performance, interobserver agreement and time for scanning were compared between 3D and 2D. Results: 3D had significantly higher sensitivities than 2D for predicting malignancy (78.7 % vs. 61.2 %, P < 0.01) and extrathyroidal extension (66.7 % vs. 46.4 %, P = 0.03) in malignancy. In terms of specificities, there were no statistically significant differences between 2D and 3D for predicting malignancy (78.4 % vs. 74.8 %, P = 1.00) and extrathyroidal extension (63.6 % vs. 57.6 %, P = 0.46). With respect to interobserver agreement, 3D showed moderate agreement (κ = 0.53) for predicting extrathyroidal extension in malignancy compared with 2D ultrasound, which showed fair agreement (κ = 0.37). 3D saved time (30 ± 56.52 s) for scanning compared with 2D. Conclusion: For off-site evaluation, 3D US is more useful for diagnosis of thyroid nodules than 2D US. Key Points: • 3D had higher sensitivity than 2D for predicting malignancy and extrathyroidal extension. • 3D showed better agreement for predicting extrathyroidal extension in malignancy than 2D. • 3D thyroid ultrasound saved time for scanning compared with 2D. • For off-site evaluation of thyroid nodules, 3D is more useful than 2D.

AB - Objectives: We compared the diagnostic performance of off-site evaluation between prospectively obtained 3D and 2D ultrasound for thyroid nodules. Methods: 3D and 2D ultrasonographies were preoperatively obtained from 85 consecutive patients (mean age, 51 years; age range, 28–83 years) who were referred for a total thyroidectomy. Three radiologists independently evaluated 3D and 2D images of 91 pathologically confirmed thyroid nodules (30 benign and 61 malignant nodules) for nodule characterization. Diagnostic performance, interobserver agreement and time for scanning were compared between 3D and 2D. Results: 3D had significantly higher sensitivities than 2D for predicting malignancy (78.7 % vs. 61.2 %, P < 0.01) and extrathyroidal extension (66.7 % vs. 46.4 %, P = 0.03) in malignancy. In terms of specificities, there were no statistically significant differences between 2D and 3D for predicting malignancy (78.4 % vs. 74.8 %, P = 1.00) and extrathyroidal extension (63.6 % vs. 57.6 %, P = 0.46). With respect to interobserver agreement, 3D showed moderate agreement (κ = 0.53) for predicting extrathyroidal extension in malignancy compared with 2D ultrasound, which showed fair agreement (κ = 0.37). 3D saved time (30 ± 56.52 s) for scanning compared with 2D. Conclusion: For off-site evaluation, 3D US is more useful for diagnosis of thyroid nodules than 2D US. Key Points: • 3D had higher sensitivity than 2D for predicting malignancy and extrathyroidal extension. • 3D showed better agreement for predicting extrathyroidal extension in malignancy than 2D. • 3D thyroid ultrasound saved time for scanning compared with 2D. • For off-site evaluation of thyroid nodules, 3D is more useful than 2D.

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