One-Pot Photochemical Synthesis of Gold Nanoplates Using Nonionic Diblock Copolymers and their Surface Functionalization

Ju Hwan Oh, Jae-Seung Lee

Research output: Contribution to journalArticle

Abstract

Two-dimensional gold nanoplates (AuNPLs) have been of significant interest because they are ideal substrates for surface modification and surface-enhanced Raman spectroscopy. Conventionally, AuNPLs are synthesized using a seed-mediated growth method employing cetyltrimethylammonium bromide (CTAB) as a shape-directing agent (SDA). The CTAB-based method, however, suffers from cumbersome multistep growth, unsuccessful surface modification, and high cytotoxicity. Therefore, the development of facile and CTAB-free synthesis of AuNPLs is required to address these challenges. Herein, we present a one-pot photochemical synthesis of AuNPLs with an average diameter of 1.5 μm using a nonionic diblock copolymer, Brij-58, as both an SDA and a reductant. The growth of AuNPLs is thermodynamically and kinetically investigated by controlling the reactant concentrations, reaction temperatures, and head-to-tail ratios of Brij polymers. Furthermore, the synthesis is conducted in the presence of seed particles, resulting in a larger diversity of structures. Notably, the obtained AuNPLs are successively conjugated with thiolated DNA, thus demonstrating the surface potential of the AuNPLs as a reversible assembly platform for bioanalytical applications.

Original languageEnglish
Pages (from-to)1165-1170
Number of pages6
JournalBulletin of the Korean Chemical Society
Volume39
Issue number10
DOIs
Publication statusPublished - 2018 Oct 1

Fingerprint

Gold
Block copolymers
Seed
Surface treatment
Cetomacrogol
Reducing Agents
Cytotoxicity
Raman spectroscopy
Polymers
DNA
Substrates
cetrimonium
Temperature

Keywords

  • Copolymer
  • Functionalization
  • Nanoplates
  • Photochemistry
  • Surface

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

@article{78c8589db57440399280cffb067ab607,
title = "One-Pot Photochemical Synthesis of Gold Nanoplates Using Nonionic Diblock Copolymers and their Surface Functionalization",
abstract = "Two-dimensional gold nanoplates (AuNPLs) have been of significant interest because they are ideal substrates for surface modification and surface-enhanced Raman spectroscopy. Conventionally, AuNPLs are synthesized using a seed-mediated growth method employing cetyltrimethylammonium bromide (CTAB) as a shape-directing agent (SDA). The CTAB-based method, however, suffers from cumbersome multistep growth, unsuccessful surface modification, and high cytotoxicity. Therefore, the development of facile and CTAB-free synthesis of AuNPLs is required to address these challenges. Herein, we present a one-pot photochemical synthesis of AuNPLs with an average diameter of 1.5 μm using a nonionic diblock copolymer, Brij-58, as both an SDA and a reductant. The growth of AuNPLs is thermodynamically and kinetically investigated by controlling the reactant concentrations, reaction temperatures, and head-to-tail ratios of Brij polymers. Furthermore, the synthesis is conducted in the presence of seed particles, resulting in a larger diversity of structures. Notably, the obtained AuNPLs are successively conjugated with thiolated DNA, thus demonstrating the surface potential of the AuNPLs as a reversible assembly platform for bioanalytical applications.",
keywords = "Copolymer, Functionalization, Nanoplates, Photochemistry, Surface",
author = "Oh, {Ju Hwan} and Jae-Seung Lee",
year = "2018",
month = "10",
day = "1",
doi = "10.1002/bkcs.11569",
language = "English",
volume = "39",
pages = "1165--1170",
journal = "Bulletin of the Korean Chemical Society",
issn = "0253-2964",
publisher = "Wiley-Blackwell",
number = "10",

}

TY - JOUR

T1 - One-Pot Photochemical Synthesis of Gold Nanoplates Using Nonionic Diblock Copolymers and their Surface Functionalization

AU - Oh, Ju Hwan

AU - Lee, Jae-Seung

PY - 2018/10/1

Y1 - 2018/10/1

N2 - Two-dimensional gold nanoplates (AuNPLs) have been of significant interest because they are ideal substrates for surface modification and surface-enhanced Raman spectroscopy. Conventionally, AuNPLs are synthesized using a seed-mediated growth method employing cetyltrimethylammonium bromide (CTAB) as a shape-directing agent (SDA). The CTAB-based method, however, suffers from cumbersome multistep growth, unsuccessful surface modification, and high cytotoxicity. Therefore, the development of facile and CTAB-free synthesis of AuNPLs is required to address these challenges. Herein, we present a one-pot photochemical synthesis of AuNPLs with an average diameter of 1.5 μm using a nonionic diblock copolymer, Brij-58, as both an SDA and a reductant. The growth of AuNPLs is thermodynamically and kinetically investigated by controlling the reactant concentrations, reaction temperatures, and head-to-tail ratios of Brij polymers. Furthermore, the synthesis is conducted in the presence of seed particles, resulting in a larger diversity of structures. Notably, the obtained AuNPLs are successively conjugated with thiolated DNA, thus demonstrating the surface potential of the AuNPLs as a reversible assembly platform for bioanalytical applications.

AB - Two-dimensional gold nanoplates (AuNPLs) have been of significant interest because they are ideal substrates for surface modification and surface-enhanced Raman spectroscopy. Conventionally, AuNPLs are synthesized using a seed-mediated growth method employing cetyltrimethylammonium bromide (CTAB) as a shape-directing agent (SDA). The CTAB-based method, however, suffers from cumbersome multistep growth, unsuccessful surface modification, and high cytotoxicity. Therefore, the development of facile and CTAB-free synthesis of AuNPLs is required to address these challenges. Herein, we present a one-pot photochemical synthesis of AuNPLs with an average diameter of 1.5 μm using a nonionic diblock copolymer, Brij-58, as both an SDA and a reductant. The growth of AuNPLs is thermodynamically and kinetically investigated by controlling the reactant concentrations, reaction temperatures, and head-to-tail ratios of Brij polymers. Furthermore, the synthesis is conducted in the presence of seed particles, resulting in a larger diversity of structures. Notably, the obtained AuNPLs are successively conjugated with thiolated DNA, thus demonstrating the surface potential of the AuNPLs as a reversible assembly platform for bioanalytical applications.

KW - Copolymer

KW - Functionalization

KW - Nanoplates

KW - Photochemistry

KW - Surface

UR - http://www.scopus.com/inward/record.url?scp=85052460716&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85052460716&partnerID=8YFLogxK

U2 - 10.1002/bkcs.11569

DO - 10.1002/bkcs.11569

M3 - Article

AN - SCOPUS:85052460716

VL - 39

SP - 1165

EP - 1170

JO - Bulletin of the Korean Chemical Society

JF - Bulletin of the Korean Chemical Society

SN - 0253-2964

IS - 10

ER -