Ophthalmoplegia with skin necrosis after a hyaluronic acid filler injection

Beom Jun Kim, Hi Jin You, Ileok Jung, Deok Woo Kim

Research output: Contribution to journalComment/debatepeer-review


Hyaluronic acid filler injection is commonly used for aesthetic purposes. However, many clinicians neglect the possibility of developing vascular occlusion and its devastating sequelae. Besides visual loss after iatrogenic ophthalmic artery occlusion, ophthalmoplegia without blindness is rare but may occur. Here, we report a 23-year-old woman with ptosis, lateral deviation of the right eye, and skin necrosis after hyaluronic acid filler injection. After hyaluronidase injection and steroid pulse therapy, ptosis and eye movement were completely restored. Skin necrosis was treated with a human epithelial growth factor ointment, followed by Nd:YAG laser. Complete healing with minimal scar was achieved.

Original languageEnglish
Pages (from-to)1307-1310
Number of pages4
JournalJournal of Cosmetic Dermatology
Issue number6
Publication statusPublished - 2020 Jun 1


  • hyaluronic acid filler
  • necrosis
  • oculomotor nerve palsy
  • ophthalmoplegia

ASJC Scopus subject areas

  • Dermatology

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