Optical resolution of RS-(±)-mandelic acid by pseudomonas sp

Byung Yong Kim, Ki Chul Hwang, Hee Sang Song, Namhyun Chung, Won Gi Bang

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

For the optical resolution of R-(-)-mandelic acid from (±)-mandelic acid, Pseudomonas sp. MA02, which assimilated S-(+)-mandelic acid as carbon and energy source, was isolated from soil. Using the fed-batch culture under optimal condition, R-(-)-mandelic acid was accumulated up to the maximum theoretical yield of 50% (30 g l-1) and entiomeric excess of 99.4%.

Original languageEnglish
Article number312873
Pages (from-to)1871-1875
Number of pages5
JournalBiotechnology letters
Volume22
Issue number23
DOIs
Publication statusPublished - 2000

Keywords

  • Fed-batch fermentation
  • Mandelic acid
  • Optical resolution
  • Pseudomonas sp

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Applied Microbiology and Biotechnology

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  • Cite this

    Kim, B. Y., Hwang, K. C., Song, H. S., Chung, N., & Bang, W. G. (2000). Optical resolution of RS-(±)-mandelic acid by pseudomonas sp. Biotechnology letters, 22(23), 1871-1875. [312873]. https://doi.org/10.1023/A:1005649908991