Optically deviated focusing method based high-speed SD-OCT for in vivo retinal clinical applications

Ruchire Eranga Wijesinghe, Kibeom Park, Pilun Kim, Jaeryung Oh, Seong Woo Kim, Kwangtae Kim, Beop Min Kim, Mansik Jeon, Jeehyun Kim

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)

Abstract

The aim of this study is to provide accurately focused, high-resolution in vivo human retinal depth images using an optically deviated focusing method with spectral-domain optical coherence tomography (SD-OCT) system. The proposed method was applied to increase the retinal diagnosing speed of patients with various values of retinal distances (i.e., the distance between the crystalline eye lens and the retina). The increased diagnosing speed was facilitated through an optical modification in the OCT sample arm configuration. Moreover, the optical path length matching process was compensated using the proposed optically deviated focusing method. The developed system was mounted on a bench-top cradle to overcome the motion artifacts. Further, we demonstrated the capability of the system by carrying out in vivo retinal imaging experiments. The clinical trials confirmed that the system was effective in diagnosing normal and abnormal retinal layers as several retinal abnormalities were identified using non-averaged single-shot OCT images, which demonstrate the feasibility of the method for clinical applications.

Original languageEnglish
Pages (from-to)307-315
Number of pages9
JournalOptical Review
Volume23
Issue number2
DOIs
Publication statusPublished - 2016 Apr 1

Keywords

  • Optically deviated focusing
  • Retinal imaging
  • SD-OCT

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

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