Abstract
Objectives. The aim of this study was to investigate optimal continuous positive airway pressure (CPAP) level, to examine the factors affecting optimal CPAP level, and to develop a predictive equation for optimal CPAP level in Korean patients with obstructive sleep apnea syndrome (OSAS). Methods. A total of 202 patients with OSAS who underwent successful manual titration for CPAP treatment were included in this study. Correlations between the optimal CPAP level and baseline data including anthropometric and polysomnographic variables were analyzed. A predictive equation for optimal CPAP level was developed based on anthropometric and polysomonographic data. Results. The mean optimal CPAP level in 202 patients with OSAS was 7.8±2.3 cm H2O. The mean optimal CPAP level in the mild, moderate, and severe OSAS groups was 6.0±1.3, 7.4±1.9, and 9.1±2.1 cm H2O, respectively. The apneahypopnea index (AHI) (r=0.595, P<0.001), arousal index (r=0.542, P<0.001), minimal SaO2 (r=-0.502, P<0.001), body mass index (BMI) (r=0.494, P<0.001), neck circumference (r=0.265, P<0.001), and age (r=-0.164, P=0.019) were significantly correlated with optimal CPAP level. The best predictive equation according to stepwise multiple linear regression analysis was: Optimal CPAP level (cm H2O)=0.681+(0.205×BMI)+(0.040×AHI). Forty-two percent of the variance in the optimal CPAP level was explained by this equation (R2=0.42, P<0.001). Conclusion. A predictive equation for optimal CPAP level in Korean patients with OSAS was developed using AHI and BMI, which can be easily measured during the diagnostic process.
| Original language | English |
|---|---|
| Pages (from-to) | 207-211 |
| Number of pages | 5 |
| Journal | Clinical and Experimental Otorhinolaryngology |
| Volume | 3 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2010 Dec 1 |
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Keywords
- Body mass index
- Continuous positive airway pressure
- Obstructive sleep apnea syndrome
- Polysomnography
ASJC Scopus subject areas
- Otorhinolaryngology
- Surgery
Cite this
Optimal continuous positive airway pressure level in Korean patients with obstructive sleep apnea syndrome. / Choi, Ji Ho; Kim, Eun Joong; Kim, Kang Woo; Choi, June; Kwon, Soon Young; Lee, Heung Man; Kim, Tae-Hoon; Lee, Sang Hag; Shin, Chol; Lee, Seung Hoon.
In: Clinical and Experimental Otorhinolaryngology, Vol. 3, No. 4, 01.12.2010, p. 207-211.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Optimal continuous positive airway pressure level in Korean patients with obstructive sleep apnea syndrome
AU - Choi, Ji Ho
AU - Kim, Eun Joong
AU - Kim, Kang Woo
AU - Choi, June
AU - Kwon, Soon Young
AU - Lee, Heung Man
AU - Kim, Tae-Hoon
AU - Lee, Sang Hag
AU - Shin, Chol
AU - Lee, Seung Hoon
PY - 2010/12/1
Y1 - 2010/12/1
N2 - Objectives. The aim of this study was to investigate optimal continuous positive airway pressure (CPAP) level, to examine the factors affecting optimal CPAP level, and to develop a predictive equation for optimal CPAP level in Korean patients with obstructive sleep apnea syndrome (OSAS). Methods. A total of 202 patients with OSAS who underwent successful manual titration for CPAP treatment were included in this study. Correlations between the optimal CPAP level and baseline data including anthropometric and polysomnographic variables were analyzed. A predictive equation for optimal CPAP level was developed based on anthropometric and polysomonographic data. Results. The mean optimal CPAP level in 202 patients with OSAS was 7.8±2.3 cm H2O. The mean optimal CPAP level in the mild, moderate, and severe OSAS groups was 6.0±1.3, 7.4±1.9, and 9.1±2.1 cm H2O, respectively. The apneahypopnea index (AHI) (r=0.595, P<0.001), arousal index (r=0.542, P<0.001), minimal SaO2 (r=-0.502, P<0.001), body mass index (BMI) (r=0.494, P<0.001), neck circumference (r=0.265, P<0.001), and age (r=-0.164, P=0.019) were significantly correlated with optimal CPAP level. The best predictive equation according to stepwise multiple linear regression analysis was: Optimal CPAP level (cm H2O)=0.681+(0.205×BMI)+(0.040×AHI). Forty-two percent of the variance in the optimal CPAP level was explained by this equation (R2=0.42, P<0.001). Conclusion. A predictive equation for optimal CPAP level in Korean patients with OSAS was developed using AHI and BMI, which can be easily measured during the diagnostic process.
AB - Objectives. The aim of this study was to investigate optimal continuous positive airway pressure (CPAP) level, to examine the factors affecting optimal CPAP level, and to develop a predictive equation for optimal CPAP level in Korean patients with obstructive sleep apnea syndrome (OSAS). Methods. A total of 202 patients with OSAS who underwent successful manual titration for CPAP treatment were included in this study. Correlations between the optimal CPAP level and baseline data including anthropometric and polysomnographic variables were analyzed. A predictive equation for optimal CPAP level was developed based on anthropometric and polysomonographic data. Results. The mean optimal CPAP level in 202 patients with OSAS was 7.8±2.3 cm H2O. The mean optimal CPAP level in the mild, moderate, and severe OSAS groups was 6.0±1.3, 7.4±1.9, and 9.1±2.1 cm H2O, respectively. The apneahypopnea index (AHI) (r=0.595, P<0.001), arousal index (r=0.542, P<0.001), minimal SaO2 (r=-0.502, P<0.001), body mass index (BMI) (r=0.494, P<0.001), neck circumference (r=0.265, P<0.001), and age (r=-0.164, P=0.019) were significantly correlated with optimal CPAP level. The best predictive equation according to stepwise multiple linear regression analysis was: Optimal CPAP level (cm H2O)=0.681+(0.205×BMI)+(0.040×AHI). Forty-two percent of the variance in the optimal CPAP level was explained by this equation (R2=0.42, P<0.001). Conclusion. A predictive equation for optimal CPAP level in Korean patients with OSAS was developed using AHI and BMI, which can be easily measured during the diagnostic process.
KW - Body mass index
KW - Continuous positive airway pressure
KW - Obstructive sleep apnea syndrome
KW - Polysomnography
UR - http://www.scopus.com/inward/record.url?scp=78650845459&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78650845459&partnerID=8YFLogxK
U2 - 10.3342/ceo.2010.3.4.207
DO - 10.3342/ceo.2010.3.4.207
M3 - Article
C2 - 21217962
AN - SCOPUS:78650845459
VL - 3
SP - 207
EP - 211
JO - Clinical and Experimental Otorhinolaryngology
JF - Clinical and Experimental Otorhinolaryngology
SN - 1976-8710
IS - 4
ER -