Optimal level of continuous positive airway pressure: Auto-adjusting titration versus titration with a predictive equation

Seung Hoon Lee, Ji Ho Choi, Young Joon Jun, Jeong In Oh, Jong Yoon Jung, Gyu Ho Hwang, Soon Young Kwon, Heung Man Lee, Tae Hoon Kim, Sang Hag Lee

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Objectives: The aims of the present study were twofold. We sought to compare two methods of titrating the level of continuous positive airway pressure (CPAP)-auto-adjusting titration and titration using a predictive equation-with full-night manual titration used as the benchmark. We also investigated the reliability of the two methods in patients with obstructive sleep apnea syndrome (OSAS). Methods: Twenty consecutive adult patients with OSAS who had successful, full-night manual and auto-adjusting CPAP titration participated in this study. The titration pressure level was calculated with a previously developed predictive equation based on body mass index and apnea-hypopnea index. Results: The mean titration pressure levels obtained with the manual, auto-adjusting, and predictive equation methods were 9.0 ± 3.6, 9.4 ± 3.0, and 8.1 ± 1.6 cm H2O, respectively. There was a significant difference in the concordance within the range of ±2 cm H2O (p = 0.019) between both the auto-adjusting titration and the titration using the predictive equation compared to the full-night manual titration. However, there was no significant difference in the concordance within the range of ±1 cm H2O (p > 0.999). Conclusions: When compared to full-night manual titration as the standard method, auto-adjusting titration appears to be more reliable than using a predictive equation for determining the optimal CPAP level in patients with OSAS.

Original languageEnglish
Pages (from-to)339-343
Number of pages5
JournalAnnals of Otology, Rhinology and Laryngology
Volume122
Issue number5
DOIs
Publication statusPublished - 2013 May

Keywords

  • Adult
  • Body Mass Index
  • Continuous Positive Airway Pressure
  • Obstructive Sleep Apnea Syndrome
  • Polysomnography

ASJC Scopus subject areas

  • Otorhinolaryngology

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