Optimal moving angle of pusher plate in occlusive-type pulsatile blood pump

Hyuk Choi, Hwansung Lee, Jaesoon Choi, Jung Joo Lee, Kyoung Won Nam, Jun Woo Park, Yongdoo Park, Kyung Sun, Heung Man Lee

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Since the occlusive-type pulsatile extracorporeal blood pump (Twin-Pulse Life Support System; Seoul National University, Seoul, Korea) received the CE mark of the European Directives and Korea Food and Drug Administration approval (2004) for short-term applications as an extracorporeal life support system, the pump system has been tested for hemolysis. This pump system was recently upgraded with an ameliorated pusher plate to reduce hemolysis. In this study, numerical analysis and in vitro tests were performed to determine the optimal conditions for increasing the durability of the blood sac and pump output. During the simulation, the minimum sliding interface force (SIF) for the angle of the pusher plate movement (PPM) was calculated (40-70°). In the in vitro durability test, the angle of the PPM was increased gradually from 40 to 70° in 10° increments, and the mean time to failure (MTTF) of the blood sac was calculated. Fifteen tests were conducted for each case: 40, 50, 60, and 70° (n = 15 each). The MTTF of the blood sac was defined as the time when a crack of the blood sac occurred. The longer lifetime of the blood sac at 60° of the PPM (297.0 h) than that at 50° (197.6 h) was attributed to the lower SIF value (-0.13, normalized value) at 60° of the PPM.

Original languageEnglish
Pages (from-to)554-560
Number of pages7
JournalArtificial Organs
Volume34
Issue number7
DOIs
Publication statusPublished - 2010 Jul 1

Fingerprint

Blood
Pumps
Life Support Systems
Korea
Hemolysis
Durability
Drug Approval
Extracorporeal Membrane Oxygenation
United States Food and Drug Administration
Numerical analysis
Cracks
Seoul
In Vitro Techniques

Keywords

  • Angle of pusher plate movement
  • Numerical analysis
  • Occlusive-type pulsatile blood pump
  • Reliability

ASJC Scopus subject areas

  • Biomaterials
  • Biomedical Engineering
  • Bioengineering
  • Medicine (miscellaneous)

Cite this

Optimal moving angle of pusher plate in occlusive-type pulsatile blood pump. / Choi, Hyuk; Lee, Hwansung; Choi, Jaesoon; Lee, Jung Joo; Nam, Kyoung Won; Park, Jun Woo; Park, Yongdoo; Sun, Kyung; Lee, Heung Man.

In: Artificial Organs, Vol. 34, No. 7, 01.07.2010, p. 554-560.

Research output: Contribution to journalArticle

Choi, Hyuk ; Lee, Hwansung ; Choi, Jaesoon ; Lee, Jung Joo ; Nam, Kyoung Won ; Park, Jun Woo ; Park, Yongdoo ; Sun, Kyung ; Lee, Heung Man. / Optimal moving angle of pusher plate in occlusive-type pulsatile blood pump. In: Artificial Organs. 2010 ; Vol. 34, No. 7. pp. 554-560.
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