Optimal Multidetector Row CT Parameters for Evaluations of the Breast: A Phantom and Specimen Study

Ann Yi, Bo Kyoung Seo, Pyong Kon Cho, Etta D. Pisano, Ki Yeol Lee, Bo-Kyung Je, Hee Young Kim, Byung Wook Min, Gil Soo Son

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Rationale and Objectives: The use of breast computed tomography (CT) has been limited by radiation hazard and image quality. The objective of this study was to compare radiation doses and image quality for different 64-channel multidetector row CT (MDCT) parameters, and to potentially provide optimal CT parameters for breast imaging. Materials and Methods: For assessment of radiation doses, CT dose index (CTDI100) values were obtained at various x-ray tube voltages (80, 120, 140 kVp) and currents (30, 50, 100, 150, 200 mAs) using a standard CT body dose phantom. To evaluate image quality, four fresh mastectomy specimens were scanned and three radiologists graded images for overall image quality, glandular tissue-fat conspicuity, and Cooper's ligament sharpness. Statistically, linear regression analyses and multiple comparisons were used for investigation of the relationship between radiation dose, image qualities, and CT parameters. Results: CTDI100 values of ≤6 mGy were obtained at 80 kVp and any mAs, 120 kVp and 30 or 50 mAs, and 140 kVp and 30 or 50 mAs. Image quality at 80 kVp and 200 mAs, 120 kV and 50, 100, 150, or 200 mAs, and 140 kVp and all mAs values tested were significantly superior to those at 80 kVp and 30, 50, 100, or 150 mAs and 120 kV and 30 mAs (P < .05). Conclusions: Based on our results, 80 kVp and 200 mAs, 120 kVp and 50 mAs, 140 kVp and 30 mAs, or 140 kVp and 50 mAs can be used for breast MDCT scanning to reduce radiation dose and preserve image quality and 140 kVp at 30 mAs is the optimal setting.

Original languageEnglish
Pages (from-to)744-751
Number of pages8
JournalAcademic Radiology
Volume17
Issue number6
DOIs
Publication statusPublished - 2010 Jun 1

Fingerprint

Multidetector Computed Tomography
Breast
Tomography
Radiation
Mastectomy
Ligaments
Linear Models
Fats
Regression Analysis
X-Rays

Keywords

  • breast
  • computed tomography (CT)
  • multidetector row, computed tomography (CT)
  • phantom imaging, mastectomy
  • radiation exposure

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Optimal Multidetector Row CT Parameters for Evaluations of the Breast : A Phantom and Specimen Study. / Yi, Ann; Seo, Bo Kyoung; Cho, Pyong Kon; Pisano, Etta D.; Lee, Ki Yeol; Je, Bo-Kyung; Kim, Hee Young; Min, Byung Wook; Son, Gil Soo.

In: Academic Radiology, Vol. 17, No. 6, 01.06.2010, p. 744-751.

Research output: Contribution to journalArticle

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abstract = "Rationale and Objectives: The use of breast computed tomography (CT) has been limited by radiation hazard and image quality. The objective of this study was to compare radiation doses and image quality for different 64-channel multidetector row CT (MDCT) parameters, and to potentially provide optimal CT parameters for breast imaging. Materials and Methods: For assessment of radiation doses, CT dose index (CTDI100) values were obtained at various x-ray tube voltages (80, 120, 140 kVp) and currents (30, 50, 100, 150, 200 mAs) using a standard CT body dose phantom. To evaluate image quality, four fresh mastectomy specimens were scanned and three radiologists graded images for overall image quality, glandular tissue-fat conspicuity, and Cooper's ligament sharpness. Statistically, linear regression analyses and multiple comparisons were used for investigation of the relationship between radiation dose, image qualities, and CT parameters. Results: CTDI100 values of ≤6 mGy were obtained at 80 kVp and any mAs, 120 kVp and 30 or 50 mAs, and 140 kVp and 30 or 50 mAs. Image quality at 80 kVp and 200 mAs, 120 kV and 50, 100, 150, or 200 mAs, and 140 kVp and all mAs values tested were significantly superior to those at 80 kVp and 30, 50, 100, or 150 mAs and 120 kV and 30 mAs (P < .05). Conclusions: Based on our results, 80 kVp and 200 mAs, 120 kVp and 50 mAs, 140 kVp and 30 mAs, or 140 kVp and 50 mAs can be used for breast MDCT scanning to reduce radiation dose and preserve image quality and 140 kVp at 30 mAs is the optimal setting.",
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AU - Seo, Bo Kyoung

AU - Cho, Pyong Kon

AU - Pisano, Etta D.

AU - Lee, Ki Yeol

AU - Je, Bo-Kyung

AU - Kim, Hee Young

AU - Min, Byung Wook

AU - Son, Gil Soo

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KW - phantom imaging, mastectomy

KW - radiation exposure

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